Interactor 1: VAMP1 (P23763)
Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
Gene: VAMP1
Interactor 2: STX1B (P61266)
Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2)
Gene: STX1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.71 | 1.00 | 0.845 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 12093152, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SNARE~Synaptobrevin, Synaptobrevin~Syntaxin |
| Common GO terms | GO:0005484 - SNAP receptor activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006906 - vesicle fusion GO:0031201 - SNARE complex |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
