HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: ARI5B (Q14865)
AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)
Gene: ARID5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045444 - fat cell differentiation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 1188
+	Hs
		620386 GATA2_HUMAN (1-480): 0: 529: 100.00		ARI1B_HUMAN (262-622): 6.16e-45: 180: 15.51
+	Hs
		620381 GATA2_HUMAN (1-480): 0: 529: 100.00		ARI3B_HUMAN (247-575): 3.17e-43: 168: 15.65
+	Hs
		620414 GATA2_HUMAN (1-480): 0: 529: 100.00		ARI3A_HUMAN (295-571): 7.58e-43: 168: 16.15
+	Hs
		146158 GATA2_HUMAN (1-480): 0: 529: 100.00		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		620361 GATA2_HUMAN (1-480): 0: 529: 100.00		ARI4B_HUMAN (323-536): 9.31e-37: 153: 24.89
+	Hs
		620365 GATA2_HUMAN (1-480): 0: 529: 100.00		ARID2_HUMAN (312-425): 1.91e-29: 129: 27.12
+	Hs
		620534 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		ARI1B_HUMAN (262-622): 6.16e-45: 180: 15.51
+	Hs
		620525 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		ARI3B_HUMAN (247-575): 3.17e-43: 168: 15.65
+	Hs
		620563 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		ARI3A_HUMAN (295-571): 7.58e-43: 168: 16.15
+	Hs
		146159 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		798998 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		KDM5D_HUMAN (238-554): 5.35e-66: 247: 17.68
+	Hs
		978240 GATA5_HUMAN (131-446): 9.19e-69: 226: 39.12		ARI5A_HUMAN (324-594): 1.05e-52: 197: 35.02
+	Hs
		554481 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		ARI1B_HUMAN (262-622): 6.16e-45: 180: 15.51
+	Hs
		798942 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		ARI3B_HUMAN (247-575): 3.17e-43: 168: 15.65
+	Hs
		146174 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		146154 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		ARI1A_HUMAN (307-567): 1.84e-39: 162: 15.65
+	Hs
		798963 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		JARD2_HUMAN (257-462): 9.34e-37: 153: 14.16
+	Mm
		994724 GATA4_MOUSE (107-479): 4.01e-68: 226: 32.83		JARD2_MOUSE (257-462): 1.57e-37: 155: 13.24