HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 636 Hs			1 776
+	Hs
		1101942 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL1_HUMAN (1-776): 0: 909: 100.00
+	Hs
		550273 PABP1_HUMAN (1-636): 0: 571: 100.00		CUL4A_HUMAN (7-776): 0: 778: 30.41
+	Hs
		550274 PABP1_HUMAN (1-636): 0: 571: 100.00		CUL4B_HUMAN (7-776): 0: 771: 29.90
+	Hs
		550272 PABP1_HUMAN (1-636): 0: 571: 100.00		CUL3_HUMAN (9-776): 0: 746: 30.47
+	Hs
		1101945 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL4A_HUMAN (7-776): 0: 778: 30.41
+	Hs
		1101946 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL4B_HUMAN (7-776): 0: 771: 29.90
+	Hs
		550271 PABP1_HUMAN (1-636): 0: 571: 100.00		CUL2_HUMAN (13-776): 0: 718: 35.98
+	Hs
		1101944 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL3_HUMAN (9-776): 0: 746: 30.47
+	Hs
		1101943 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL2_HUMAN (13-776): 0: 718: 35.98
+	Hs
		550398 PABP1_HUMAN (1-636): 0: 571: 100.00		CUL5_HUMAN (2-776): 0: 620: 28.85
+	Hs
		1102047 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CUL5_HUMAN (2-776): 0: 620: 28.85
+	Hs
		726759 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		CUL1_HUMAN (1-776): 0: 909: 100.00
+	Hs
		620348 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CUL1_HUMAN (1-776): 0: 909: 100.00
+	Hs
		726762 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		CUL4A_HUMAN (7-776): 0: 778: 30.41
+	Hs
		726761 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		CUL3_HUMAN (9-776): 0: 746: 30.47
+	Hs
		726760 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		CUL2_HUMAN (13-776): 0: 718: 35.98
+	Mm
		480990 NUCL_MOUSE (165-384): 1.32e-20: 98.4: 19.20		CUL3_MOUSE (9-776): 0: 745: 30.35
+	Hs
		620350 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CUL3_HUMAN (9-776): 0: 746: 30.47
+	Hs
		620349 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CUL2_HUMAN (13-776): 0: 718: 35.98
+	Hs
		726787 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		CUL5_HUMAN (2-776): 0: 620: 28.85