HitPredict

Interactor 1: HXD12 (P23812)
Homeobox protein Hox-D12 (Homeobox protein Hox-4.7) (Homeobox protein Hox-5.6)
Gene: Hoxd12

Interactor 2: PO6F1 (Q07916)
POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1)
Gene: Pou6f1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain, Homeodomain~Pou
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 268 Mm			1 301
+	Mm
		620871 HXD12_MOUSE (1-268): 1.26e-61: 196: 100.00		Q5U4D4_MOUSE (1-301): 2.77e-82: 260: 100.00
+	Hs
		678898 HXC8_HUMAN (101-263): 3.25e-37: 133: 28.99		PO6F2_HUMAN (1-301): 1.43e-55: 192: 48.70
+	Hs
		540816 GSC_HUMAN (17-260): 1.02e-30: 116: 15.98		PO2F1_HUMAN (5-293): 3.2e-59: 203: 29.87
+	Mm
		453081 HXB8_MOUSE (91-264): 6.39e-33: 122: 24.75		PO2F1_MOUSE (5-293): 7.87e-57: 196: 28.71
+	Dm
		557311 UBX_DROME (52-261): 2.82e-33: 126: 22.79		CF1A_DROME (24-298): 5.22e-57: 191: 27.53
+	Mm
		453069 HXA9_MOUSE (23-262): 5.14e-32: 120: 22.99		PO2F1_MOUSE (5-293): 7.87e-57: 196: 28.71
+	Mm
		631276 HXC4_MOUSE (138-260): 3.74e-32: 120: 31.11		PO2F1_MOUSE (5-293): 7.87e-57: 196: 28.71
+	Mm
		447605 HXA6_MOUSE (70-260): 1.61e-30: 115: 21.15		PO2F1_MOUSE (5-293): 7.87e-57: 196: 28.71
+	Hs
		944014 HXC5_HUMAN (108-267): 6.48e-31: 116: 29.10		PO6F2_HUMAN (1-301): 1.43e-55: 192: 48.70
+	Dm
		185813 UBX_DROME (52-261): 2.82e-33: 126: 22.79		PAX6_DROME (3-300): 2.65e-45: 165: 14.61
+	Dm
		185797 ANTP_DROME (136-263): 4.28e-33: 125: 27.74		PAX6_DROME (3-300): 2.65e-45: 165: 14.61
+	Dm
		81147 UBX_DROME (52-261): 2.82e-33: 126: 22.79		B7YZU0_DROME (3-298): 3.27e-43: 160: 41.36
+	Hs
		567821 HXB9_HUMAN (7-265): 6.4e-33: 122: 21.84		HXA1_HUMAN (58-298): 1.05e-39: 143: 16.46
+	Dm
		950100 UBX_DROME (52-261): 2.82e-33: 126: 22.79		Q9W1H7_DROME (219-294): 3.77e-35: 128: 27.63
+	Hs
		678981 HXC8_HUMAN (101-263): 3.25e-37: 133: 28.99		HESX1_HUMAN (233-298): 5.46e-21: 89.9: 33.33
+	Hs
		960051 HXC5_HUMAN (108-267): 6.48e-31: 116: 29.10		LHX4_HUMAN (209-294): 5.06e-20: 91: 27.91
+	Hs
		1199933 VSX1_HUMAN (13-267): 1.18e-30: 119: 16.08		ZFHX4_HUMAN (235-299): 4.61e-11: 65.6: 26.15
+	Hs
		1080569 VSX1_HUMAN (13-267): 1.18e-30: 119: 16.08		ZFHX3_HUMAN (166-299): 1.82e-10: 63.7: 19.85
+	Hs
		882139 GSC_HUMAN (17-260): 1.02e-30: 116: 15.98		ZFHX4_HUMAN (235-299): 4.61e-11: 65.6: 26.15
+	Hs
		882128 GSC_HUMAN (17-260): 1.02e-30: 116: 15.98		ZFHX3_HUMAN (166-299): 1.82e-10: 63.7: 19.85