Protein: ACTN1
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)

Gene: ACTN1
Organism: Rattus norvegicus
Interactions: 19
UniProt ID: Q9Z1P2

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0001726 - ruffle
GO:0003713 - transcription coactivator activity
GO:0003725 - double-stranded RNA binding
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930659

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

4

High-throughput

0.691

High

1231096

PDLI2
PDZ and LIM domain protein 2

1

20

Small-scale

0.647

High

540210

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

6

Small-scale

0.618

High

591445

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

19

Small-scale

0.618

High

1251028

Q6XD99
Spectrin beta chain

1

18

Small-scale

0.618

High

640095

MK03
Mitogen-activated protein kinase 3

1

7

High-throughput

0.575

High

1220372

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.536

High

1491906

GIPC1
PDZ domain-containing protein GIPC1

1

1

Small-scale

0.506

High

93241

D4A435
Intercellular adhesion molecule 5

1

14

Small-scale

0.479

High

204587

NEB2
Neurabin-2

1

20

Small-scale

0.479

High

465305

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

618303

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

4

Small-scale

0.479

High

726634

GRM5
Metabotropic glutamate receptor 5

1

3

Small-scale

0.479

High

771532

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

9

Small-scale

0.479

High

1010187

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.479

High

1224564

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

3

High-throughput

0.479

High

1353926

Q8VD38
Transient receptor potential cation channel subfamily C member 5

1

6

Small-scale

0.479

High

1408919

Q99N78
Transient receptor potential Ca2+ channel 6A

1

9

Small-scale

0.479

High

621330

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

3

High-throughput

0.445

High


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Last updated: 11Aug2025