HitPredict

Interactor 1: GRIA1 (P23818)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)
Gene: GRIA1

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0030425 - dendrite GO:0035255 - ionotropic glutamate receptor binding GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 907 Mm			1 1186
+	Rn
		585155 GRIA1_RAT (1-907): 0: 939: 98.90		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Mm
		100188 F6YNQ1_MOUSE (70-907): 0: 869: 100.00		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		620948 GRIA2_MOUSE (6-840): 0: 829: 70.71		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Rn
		585178 GRIA2_RAT (6-840): 0: 828: 70.71		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Hs
		786742 GRIA2_HUMAN (6-840): 0: 831: 70.83		AGAP2_HUMAN (1-1147): 0: 987: 94.10
+	Mm
		723576 NMDZ1_MOUSE (1-906): 0: 575: 21.83		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		723556 NMDZ1_MOUSE (1-906): 0: 575: 21.83		RAP1A_MOUSE (398-567): 1.81e-70: 235: 23.03