HitPredict

Interactor 1: FSHR (P23945)
Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor)
Gene: FSHR

Interactor 2: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0043235 - receptor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 695 Hs			1 532
+	Hs
		723275 APJ_HUMAN (340-667): 4.64e-62: 213: 19.05		BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00
+	At
		1167634 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		BRL3_ARATH (43-526): 8.06e-143: 442: 18.22
+	At
		1167645 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		BRL1_ARATH (43-530): 1.44e-142: 441: 18.24
+	At
		1167625 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		IOS1_ARATH (1-528): 5.2e-145: 440: 15.04
+	At
		1167642 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		Y2451_ARATH (1-526): 1.29e-142: 433: 16.88
+	At
		186962 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		BRI1_ARATH (24-525): 5.01e-136: 425: 14.91
+	At
		84147 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		Y2289_ARATH (1-531): 6.14e-138: 422: 15.16
+	At
		1325556 Y1571_ARATH (1-340): 2.1e-54: 204: 12.88		Y5181_ARATH (1-531): 8.06e-147: 445: 17.32
+	At
		84489 GSO1_ARATH (1-310): 2.54e-55: 207: 15.50		BRL3_ARATH (43-526): 8.06e-143: 442: 18.22
+	At
		84511 GSO1_ARATH (1-310): 2.54e-55: 207: 15.50		BRL1_ARATH (43-530): 1.44e-142: 441: 18.24
+	At
		1167616 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		NIK2_ARATH (11-523): 4.51e-138: 415: 15.49
+	At
		83510 Y1571_ARATH (1-340): 2.1e-54: 204: 12.88		Y1756_ARATH (1-529): 3.63e-145: 440: 17.06
+	At
		1167621 ERL2_ARATH (1-396): 8.93e-64: 230: 12.87		BAK1_ARATH (3-523): 5.27e-137: 411: 15.44
+	At
		84526 Y1571_ARATH (1-340): 2.1e-54: 204: 12.88		Y4245_ARATH (1-531): 3.85e-141: 431: 15.87
+	At
		1013325 Y1571_ARATH (1-340): 2.1e-54: 204: 12.88		Y2239_ARATH (18-523): 2.7e-139: 418: 17.19
+	At
		84475 GSO1_ARATH (1-310): 2.54e-55: 207: 15.50		NIK2_ARATH (11-523): 4.51e-138: 415: 15.49
+	At
		84471 GSO1_ARATH (1-310): 2.54e-55: 207: 15.50		Q8GX94_ARATH (21-530): 1.2e-137: 412: 16.07
+	At
		84479 GSO1_ARATH (1-310): 2.54e-55: 207: 15.50		BAK1_ARATH (3-523): 5.27e-137: 411: 15.44
+	Mm
		192377 OPSX_MOUSE (360-647): 1e-65: 222: 21.45		TGFR2_MOUSE (35-528): 7.09e-120: 366: 28.63
+	Hs
		646073 FLRT1_HUMAN (3-310): 1.3e-60: 217: 20.13		AVR2A_HUMAN (81-530): 3.08e-111: 341: 32.56