HitPredict

Interactor 1: PEX1 (P24004)
Peroxisomal ATPase PEX1 (EC 3.6.4.-) (Peroxin-1) (Peroxisomal assembly protein 1) (Peroxisome biogenesis protein PAS1)
Gene: PEX1

Interactor 2: PEX6 (P33760)
Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal assembly protein 8)
Gene: PEX6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 11283351, 16007078, 25659908, 26066397, 26170309, 15634331, 26842748, 29321502, 30097517, 18719252, 37741838, 37968396, 38036174, 22710083, 22500805, 22940862, unassigned1933, 16911527
Identification Methods two hybrid pooling approach, affinity chromatography technology, pull down, x-ray crystallography, two hybrid, biochemical, protein complementation assay, dihydrofolate reductase reconstruction, bimolecular fluorescence complementation, blue native page
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3
Common GO terms GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005829 - cytosol
GO:0016558 - protein import into peroxisome matrix
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1043
Sc

1 1030
+ Dm
+ At
+ Ce
+ Sc
+ Sc
+ Ce
+ Sc
+ Rn
+ Hs
+ Mm
+ Ce
+ Hs
+ At
+ Hs
+ Sp
+ Hs
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024