HitPredict

Interactor 1: RAE1 (P24386)
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)
Gene: CHM

Interactor 2: RB33A (Q14088)
Ras-related protein Rab-33A (Small GTP-binding protein S10)
Gene: RAB33A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 237
+	Hs
		622617 RAE1_HUMAN (1-653): 0: 996: 100.00		RB33B_HUMAN (30-237): 9.32e-89: 263: 61.06
+	Hs
		622577 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB1A_HUMAN (27-235): 9.54e-87: 257: 40.19
+	Hs
		622586 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB35_HUMAN (36-237): 4.32e-86: 255: 46.80
+	Hs
		622619 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB1B_HUMAN (29-236): 4.49e-83: 247: 38.46
+	Hs
		622570 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8A_HUMAN (29-237): 2.57e-80: 241: 36.84
+	Hs
		622576 RAE1_HUMAN (1-653): 0: 996: 100.00		RB11A_HUMAN (27-236): 1.27e-79: 239: 32.26
+	Hs
		622608 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8B_HUMAN (29-237): 3.86e-79: 238: 36.84
+	Hs
		642727 RAE2_HUMAN (1-650): 0: 938: 71.98		RB33A_HUMAN (1-237): 1.2e-93: 276: 100.00
+	Hs
		642723 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB1A_HUMAN (27-235): 9.54e-87: 257: 40.19
+	Hs
		642728 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB35_HUMAN (36-237): 4.32e-86: 255: 46.80
+	Hs
		642743 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB1B_HUMAN (29-236): 4.49e-83: 247: 38.46
+	Hs
		642718 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB8A_HUMAN (29-237): 2.57e-80: 241: 36.84
+	Hs
		642722 RAE2_HUMAN (1-650): 0: 938: 71.98		RB11A_HUMAN (27-236): 1.27e-79: 239: 32.26
+	Hs
		642738 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB8B_HUMAN (29-237): 3.86e-79: 238: 36.84
+	Hs
		622589 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB30_HUMAN (36-205): 1.87e-50: 165: 51.18
+	Hs
		642729 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB30_HUMAN (36-205): 1.87e-50: 165: 51.18
+	Hs
		678344 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB1A_HUMAN (27-235): 9.54e-87: 257: 40.19
+	Hs
		678336 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB8A_HUMAN (29-237): 2.57e-80: 241: 36.84
+	Hs
		678343 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RB11A_HUMAN (27-236): 1.27e-79: 239: 32.26
+	Hs
		678333 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB13_HUMAN (36-233): 1.95e-44: 149: 41.92