HitPredict

Interactor 1: COT2 (P24468)
COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)
Gene: NR2F2

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15140878
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0042803 - protein homodimerization activity GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 299
+	Hs
		490112 COT1_HUMAN (1-414): 7.68e-137: 399: 84.98		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		320222 ERR2_HUMAN (18-403): 2.16e-104: 317: 28.43		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		370282 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		320178 ERR2_HUMAN (18-403): 2.16e-104: 317: 28.43		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		369087 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		369022 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		824306 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		718614 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646143 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93