HitPredict

Interactor 1: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Interactor 2: H11 (Q02539)
Histone H1.1 (Histone H1a)
Gene: H1-1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.757

Property	Details
Experiments	11160398, 10393546, 9840927, 22158041, 9632134, 9380407, 9053846, 8647086, 11940657, 9885575, 9886493
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 215
+	Hs
		558989 CCNE1_HUMAN (1-410): 2.36e-135: 395: 100.00		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Rn
		70079 B1WC54_RAT (1-408): 4.27e-125: 369: 79.95		H11_RAT (1-123): 9.41e-24: 95.9: 77.24
+	Hs
		558984 CCNA2_HUMAN (2-369): 1.62e-99: 304: 20.58		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		590167 CCNA2_HUMAN (2-369): 1.62e-99: 304: 20.58		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Hs
		559062 CCNA1_HUMAN (15-367): 4.41e-96: 297: 20.98		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Rn
		88902 CCNA1_RAT (4-369): 3.44e-95: 293: 21.12		H11_RAT (1-123): 9.41e-24: 95.9: 77.24
+	Hs
		538465 CCNB1_HUMAN (1-365): 5.55e-95: 293: 18.82		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		331638 CCNE2_HUMAN (4-402): 7.36e-97: 297: 47.38		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Hs
		943775 CCNA1_HUMAN (15-367): 4.41e-96: 297: 20.98		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Hs
		538525 CCNB1_HUMAN (1-365): 5.55e-95: 293: 18.82		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Mm
		624386 CCNB1_MOUSE (4-362): 8.4e-94: 290: 18.33		H11_MOUSE (1-124): 1.61e-17: 79.4: 79.84