HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: GPN3 (Q9UHW5)
GPN-loop GTPase 3 (ATP-binding domain 1 family member C)
Gene: GPN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1970 Hs			1 284
+	Hs
		625054 RPB1_HUMAN (1-1611): 0: 1858: 100.00		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		375512 RPB1_YEAST (11-1592): 0: 1458: 48.49		GPN3_YEAST (1-268): 5.79e-122: 351: 43.17
+	Hs
		156080 RPC1_HUMAN (16-1484): 0: 1349: 33.36		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Sc
		375435 RPB1_YEAST (11-1592): 0: 1458: 48.49		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Hs
		156069 RPC1_HUMAN (16-1484): 0: 1349: 33.36		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		375618 RPC1_YEAST (11-1471): 0: 1356: 32.85		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Sc
		501383 RPA1_YEAST (11-1472): 0: 1134: 22.98		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Hs
		317182 RPA1_HUMAN (960-1473): 4.35e-38: 159: 16.12		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Hs
		317164 RPA1_HUMAN (960-1473): 4.35e-38: 159: 16.12		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40