Interactor 1: SPTC1 (P25045)
Serine palmitoyltransferase 1 (SPT 1) (SPT1) (EC 2.3.1.50) (Long chain base biosynthesis protein 1)
Gene: LCB1

Interactor 2: ORM1 (P53224)
Protein ORM1
Gene: ORM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.944

The method score is based on:

Property Details
Experiments 20212121, 20182505, 30529276, 37794019, 37982431, 23363605
Identification Methods pull down, anti tag coimmunoprecipitation, protein complementation assay, biochemical, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_1_2~ORMDL
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0090156 - intracellular sphingolipid homeostasis
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 558
Sc

1 222
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024