Interactor 1: SPTC1 (P25045)
Serine palmitoyltransferase 1 (SPT 1) (SPT1) (EC 2.3.1.50) (Long chain base biosynthesis protein 1)
Gene: LCB1

Interactor 2: TSC3 (Q3E790)
Serine palmitoyltransferase-regulating protein TSC3 (Temperature-sensitive CSG2-mutant suppressor protein 3)
Gene: TSC3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 20182505, 37968396, 38285738, 10713067, 30529276, 37794019, 37982431
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0090156 - intracellular sphingolipid homeostasis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 558
Sc

1 80
+ Sc

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Last updated: 15 Jul 2024