Protein: LIPG
Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL) (Phospholipase A1) (EC 3.1.1.32)

Gene: LIPG
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9Y5X9

Gene Ontology (top 5):
GO:0004620 - phospholipase activity
GO:0004465 - lipoprotein lipase activity
GO:0004806 - triacylglycerol lipase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

889054

TMEDA
Transmembrane emp24 domain-containing protein 10

2

4

High-throughput

0.628

High

1146665

TMED2
Transmembrane emp24 domain-containing protein 2

2

5

High-throughput

0.628

High

1281284

TMED4
Transmembrane emp24 domain-containing protein 4

2

3

High-throughput

0.628

High

1415437

TMED9
Transmembrane emp24 domain-containing protein 9

2

3

High-throughput

0.628

High

1491123

TMED5
Transmembrane emp24 domain-containing protein 5

2

5

High-throughput

0.628

High

1491771

LIPG
Endothelial lipase

1

12

Small-scale

0.618

High

164486

NRP1
Neuropilin-1

2

0

High-throughput

0.602

High

521056

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

0

High-throughput

0.602

High

1102780

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

0

High-throughput

0.602

High

1158213

MK14
Mitogen-activated protein kinase 14

2

0

High-throughput

0.602

High

699296

CALX
Calnexin

2

3

High-throughput

0.574

High

1433430

TBB1
Tubulin beta-1 chain

2

1

High-throughput

0.574

High

1452044

TRM1
tRNA

2

1

High-throughput

0.574

High

274935

LRP5
Low-density lipoprotein receptor-related protein 5

1

6

High-throughput

0.536

High

324066

CSTN1
Calsyntenin-1

1

1

High-throughput

0.536

High

376567

LDLR
Low-density lipoprotein receptor

1

6

High-throughput

0.536

High

472214

TRFM
Melanotransferrin

1

3

High-throughput

0.536

High

554275

BMP4
Bone morphogenetic protein 4

1

2

High-throughput

0.536

High

566891

PDIA4
Protein disulfide-isomerase A4

1

3

High-throughput

0.536

High

626038

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

2

High-throughput

0.536

High

648755

FGFR4
Fibroblast growth factor receptor 4

1

2

High-throughput

0.536

High

650515

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.536

High

937456

LAMB2
Laminin subunit beta-2

1

3

High-throughput

0.536

High

1105885

TMED1
Transmembrane emp24 domain-containing protein 1

1

5

High-throughput

0.536

High

1248939

ARSK
Arylsulfatase K

1

2

High-throughput

0.536

High

1388954

ARSG
Arylsulfatase G

1

2

High-throughput

0.536

High

1491422

LOXL2
Lysyl oxidase homolog 2

1

2

High-throughput

0.536

High

1491772

AGRG1
Adhesion G-protein coupled receptor G1

1

1

High-throughput

0.536

High

760519

SDC2
Syndecan-2

1

0

High-throughput

0.513

High

876293

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.513

High

906378

GPC3
Glypican-3

1

0

High-throughput

0.513

High

1089136

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

1225420

METRL
Meteorin-like protein

1

0

High-throughput

0.513

High

1243288

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

0

High-throughput

0.513

High

160846

TOR1B
Torsin-1B

1

2

High-throughput

0.489

High

876749

HSP13
Heat shock 70 kDa protein 13

1

1

High-throughput

0.489

High

909264

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

1022507

IDD
Integral membrane protein DGCR2/IDD

1

7

High-throughput

0.489

High

1143707

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.489

High

1212710

GT253
Inactive glycosyltransferase 25 family member 3

1

1

High-throughput

0.489

High

1308863

P3H3
Prolyl 3-hydroxylase 3

1

2

High-throughput

0.489

High

1333644

SUMF1
Formylglycine-generating enzyme

1

1

High-throughput

0.489

High

1352562

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.489

High

1368442

SC65
Endoplasmic reticulum protein SC65

1

2

High-throughput

0.489

High

1384781

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.489

High

1399807

RBM14
RNA-binding protein 14

1

1

High-throughput

0.489

High

1433304

TOR3A
Torsin-3A

1

2

High-throughput

0.489

High

1490436

JAG2
Protein jagged-2

1

1

High-throughput

0.489

High

273602

DJC13
DnaJ homolog subfamily C member 13

2

0

High-throughput

0.328

High

1129136

PLSI
Plastin-1

2

0

High-throughput

0.328

High

1414305

ABHEA
Protein ABHD14A

2

0

High-throughput

0.328

High

164750

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

1034855

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1333667

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

1334428

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

1348879

AT2L1
Ethanolamine-phosphate phospho-lyase

1

0

High-throughput

0.279

Low

1388131

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1415056

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.279

Low

1448148

CHSTC
Carbohydrate sulfotransferase 12

1

0

High-throughput

0.279

Low

1452022

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.279

Low

1459716

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

1490692

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low

1447251

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.265

Low

187582

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025