HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	20936779, 26496610
Identification Methods	two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 432
+	Hs
		359304 APC_HUMAN (1-2843): 0: 1316: 100.00		K1C14_HUMAN (82-430): 1.15e-151: 440: 82.40
+	Hs
		444317 APC_HUMAN (1-2843): 0: 1316: 100.00		K1C19_HUMAN (77-394): 1.39e-146: 424: 73.59
+	Hs
		531447 APC_HUMAN (1-2843): 0: 1316: 100.00		K1C13_HUMAN (73-398): 8.48e-143: 417: 70.73
+	Hs
		579993 APC_HUMAN (1-2843): 0: 1316: 100.00		K1C15_HUMAN (83-426): 2.02e-141: 413: 68.66
+	Hs
		531535 APC_HUMAN (1-2843): 0: 1316: 100.00		K2C5_HUMAN (50-398): 1.34e-72: 240: 25.07
+	Hs
		280854 APC_HUMAN (1-2843): 0: 1316: 100.00		KRT37_HUMAN (1-395): 7.16e-72: 235: 43.75
+	Hs
		280953 APC_HUMAN (1-2843): 0: 1316: 100.00		KRT38_HUMAN (1-395): 1.59e-71: 234: 44.50
+	Hs
		1205250 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		K2C73_HUMAN (4-398): 3.6e-88: 279: 25.68