Protein: ASB3
Ankyrin repeat and SOCS box protein 3 (ASB-3)

Gene: ASB3
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q9Y575

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1371912

CUL5
Cullin-5

7

16

Small-scale

0.965

High

1147159

ELOC
Elongin-C

5

4

Small-scale

0.925

High

1445803

SH22A
SH2 domain-containing protein 2A

2

10

High-throughput

0.819

High

67723

RHG32
Rho GTPase-activating protein 32

2

5

High-throughput

0.811

High

1451442

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

2

15

High-throughput

0.811

High

896477

ERF
ETS domain-containing transcription factor ERF

2

0

High-throughput

0.770

High

1202610

TNI3K
Serine/threonine-protein kinase TNNI3K

2

16

High-throughput

0.726

High

1412936

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

4

High-throughput

0.700

High

849089

ZAP70
Tyrosine-protein kinase ZAP-70

1

14

High-throughput

0.698

High

239343

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

20

High-throughput

0.691

High

1399264

SAM11
Sterile alpha motif domain-containing protein 11

2

0

High-throughput

0.679

High

1224942

TENS2
Tensin-2

2

4

High-throughput

0.665

High

1448595

DISC1
Disrupted in schizophrenia 1 protein

3

6

High-throughput

0.665

High

1147320

ELOB
Elongin-B

3

4

Small-scale

0.640

High

1039593

TOP2B
DNA topoisomerase 2-beta

2

3

High-throughput

0.628

High

1308735

FOXP4
Forkhead box protein P4

2

5

High-throughput

0.628

High

1365707

LAR4B
La-related protein 4B

2

3

High-throughput

0.628

High

1415104

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

2

8

High-throughput

0.628

High

1448134

4ET
Eukaryotic translation initiation factor 4E transporter

2

2

High-throughput

0.628

High

282507

KTNA1
Katanin p60 ATPase-containing subunit A1

1

18

High-throughput

0.618

High

1289783

ZBT46
Zinc finger and BTB domain-containing protein 46

1

1

High-throughput

0.618

High

193317

SOCS1
Suppressor of cytokine signaling 1

1

9

Small-scale

0.618

High

1115171

CUL4A
Cullin-4A

1

16

High-throughput

0.618

High

1451560

ASB6
Ankyrin repeat and SOCS box protein 6

1

19

High-throughput

0.618

High

630386

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

5

Small-scale

0.617

High

67515

ZSWM8
Zinc finger SWIM domain-containing protein 8

2

0

High-throughput

0.602

High

1218239

ZN318
Zinc finger protein 318

2

0

High-throughput

0.602

High

246199

KIF1B
Kinesin-like protein KIF1B

1

4

High-throughput

0.594

High

944120

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

19

High-throughput

0.590

High

1398744

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

1347908

RIN3
Ras and Rab interactor 3

2

4

High-throughput

0.576

High

542709

TOP2A
DNA topoisomerase 2-alpha

2

2

High-throughput

0.574

High

1258224

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

1

High-throughput

0.574

High

1433495

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

16

High-throughput

0.555

High

1061930

TLE5
TLE family member 5

2

2

High-throughput

0.553

High

1125095

RCN2
Reticulocalbin-2

1

3

High-throughput

0.553

High

984039

RBX1
E3 ubiquitin-protein ligase RBX1

1

4

High-throughput

0.536

High

1094452

CSN1
COP9 signalosome complex subunit 1

1

1

High-throughput

0.536

High

1247063

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.536

High

1277722

MYCPP
C-myc promoter-binding protein

1

3

High-throughput

0.536

High

1391984

DCNL1
DCN1-like protein 1

1

1

High-throughput

0.536

High

1406531

ATX2
Ataxin-2

1

10

High-throughput

0.536

High

1458376

RBX2
RING-box protein 2

1

4

High-throughput

0.536

High

167424

KLF11
Krueppel-like factor 11

1

6

High-throughput

0.515

High

243405

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.515

High

415963

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.515

High

451303

NFL
Neurofilament light polypeptide

1

19

High-throughput

0.515

High

570643

GFAP
Glial fibrillary acidic protein

1

19

High-throughput

0.515

High

844136

HD
Huntingtin

1

2

High-throughput

0.515

High

857003

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.515

High

905338

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.515

High

927634

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

954649

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

2

High-throughput

0.515

High

1199415

GLE1
mRNA export factor GLE1

1

7

High-throughput

0.515

High

1279812

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

3

High-throughput

0.515

High

508899

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

216857

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

713148

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.493

High

822928

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

898552

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.493

High

927188

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

1347788

F110D
Protein FAM110D

1

1

High-throughput

0.489

High

335208

ARI2
E3 ubiquitin-protein ligase ARIH2

1

5

High-throughput

0.479

High

424295

S10A8
Protein S100-A8

1

4

High-throughput

0.479

High

445105

S10A9
Protein S100-A9

1

4

High-throughput

0.479

High

462084

HS90A
Heat shock protein HSP 90-alpha

1

16

High-throughput

0.479

High

468955

HS90B
Heat shock protein HSP 90-beta

1

16

High-throughput

0.479

High

655387

SFPQ
Splicing factor, proline- and glutamine-rich

1

5

High-throughput

0.479

High

716366

PRDX6
Peroxiredoxin-6

1

5

High-throughput

0.479

High

772640

GDE
Glycogen debranching enzyme

1

1

High-throughput

0.479

High

840839

RS27
Small ribosomal subunit protein eS27

1

4

High-throughput

0.479

High

1090995

TRAF2
TNF receptor-associated factor 2

1

12

Small-scale

0.479

High

1490789

E41L3
Band 4.1-like protein 3

1

20

High-throughput

0.479

High

109540

G5E9A7
DM1 locus, WD repeat containing

1

10

High-throughput

0.470

High

301778

WFS1
Wolframin

1

1

High-throughput

0.470

High

1096290

TADBP
TAR DNA-binding protein 43

1

3

High-throughput

0.470

High

1360783

JPH3
Junctophilin-3

1

2

High-throughput

0.470

High

1491174

RNF11
RING finger protein 11

1

2

High-throughput

0.470

High

247056

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.464

High

1396950

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.464

High

270996

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.458

High

788833

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.458

High

992120

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

1461480

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.458

High

1227781

A16L1
Autophagy-related protein 16-1

1

12

High-throughput

0.445

High

533806

CLUS
Clusterin

1

0

High-throughput

0.438

High

425086

ADT2
ADP/ATP translocase 2

1

11

High-throughput

0.437

High

784774

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

3

High-throughput

0.437

High

1015344

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.437

High

1144512

NONO
Non-POU domain-containing octamer-binding protein

1

6

High-throughput

0.437

High

1393525

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

2

High-throughput

0.437

High

1401472

CIC
Protein capicua homolog

1

19

High-throughput

0.437

High

1416399

NADAP
Kanadaptin

1

4

High-throughput

0.437

High

1452583

BCLF1
Bcl-2-associated transcription factor 1

1

11

High-throughput

0.437

High

1490959

TR150
Thyroid hormone receptor-associated protein 3

1

14

High-throughput

0.437

High

947086

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

1187994

GON4L
GON-4-like protein

2

0

High-throughput

0.328

High

1395322

LCOR
Ligand-dependent corepressor

2

0

High-throughput

0.328

High

1417945

K1671
Uncharacterized protein KIAA1671

2

0

High-throughput

0.328

High

1462607

SATB2
DNA-binding protein SATB2

2

0

High-throughput

0.328

High

1491331

SALL2
Sal-like protein 2

2

0

High-throughput

0.328

High

1430151

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

891948

WHR1
Winged helix repair factor 1

1

0

High-throughput

0.279

Low

1086524

TROAP
Tastin

1

0

High-throughput

0.279

Low

1103119

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

1130685

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.279

Low

1208249

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1451216

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.279

Low

389906

TTHY
Transthyretin

1

0

High-throughput

0.268

Low

458945

HEXB
Beta-hexosaminidase subunit beta

1

0

High-throughput

0.268

Low

622309

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

705623

GRN
Progranulin

1

0

High-throughput

0.268

Low

665756

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025