Interactor 1: TNR1A (P25118)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a)
Gene: Tnfrsf1a

Interactor 2: BIRC2 (Q62210)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2) (RING-type E3 ubiquitin transferase BIRC2)
Gene: BIRC2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 18022363
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~Death
Common GO terms GO:0032991 - protein-containing complex
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0043066 - negative regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0044877 - protein-containing complex binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 454
Mm

1 612
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024