HitPredict

Interactor 1: CCND1 (P25322)
G1/S-specific cyclin-D1
Gene: CCND1

Interactor 2: PP1G (P63087)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: Ppp1cc

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17274640
Identification Methods	affinity chromatography technology, antibody array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0030182 - neuron differentiation GO:0044877 - protein-containing complex binding and 1 others more... GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 295 Mm			1 323
+	Hs
		538485 CCNB1_HUMAN (4-279): 7.33e-90: 275: 20.36		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Mm
		624389 CCNB1_MOUSE (5-280): 7.61e-88: 270: 18.71		PP1G_MOUSE (1-323): 0: 601: 100.00
+	Hs
		905830 CCNA1_HUMAN (9-278): 1.66e-93: 286: 24.00		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Mm
		906272 CCNA1_MOUSE (12-278): 1.02e-91: 279: 24.27		PP1A_MOUSE (1-323): 0: 578: 90.36
+	Mm
		673184 CCND3_MOUSE (4-295): 9.1e-84: 255: 50.51		PP1G_MOUSE (1-323): 0: 601: 100.00
+	Hs
		538508 CCNB1_HUMAN (4-279): 7.33e-90: 275: 20.36		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Mm
		624387 CCNB1_MOUSE (5-280): 7.61e-88: 270: 18.71		PP1A_MOUSE (1-323): 0: 578: 90.36
+	Hs
		622375 CCND1_HUMAN (1-295): 2.75e-77: 239: 93.90		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Hs
		673126 CCND3_HUMAN (3-295): 2.4e-76: 236: 51.35		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Hs
		538509 CCNB1_HUMAN (4-279): 7.33e-90: 275: 20.36		PP1B_HUMAN (1-322): 0: 559: 86.89
+	Mm
		673182 CCND3_MOUSE (4-295): 9.1e-84: 255: 50.51		PP1A_MOUSE (1-323): 0: 578: 90.36
+	Mm
		624388 CCNB1_MOUSE (5-280): 7.61e-88: 270: 18.71		PP1B_MOUSE (1-322): 0: 559: 86.89
+	Hs
		673135 CCND3_HUMAN (3-295): 2.4e-76: 236: 51.35		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Mm
		673183 CCND3_MOUSE (4-295): 9.1e-84: 255: 50.51		PP1B_MOUSE (1-322): 0: 559: 86.89
+	Hs
		622421 CCND1_HUMAN (1-295): 2.75e-77: 239: 93.90		PP1B_HUMAN (1-322): 0: 559: 86.89
+	Hs
		673136 CCND3_HUMAN (3-295): 2.4e-76: 236: 51.35		PP1B_HUMAN (1-322): 0: 559: 86.89
+	Hs
		915161 CCNA1_HUMAN (9-278): 1.66e-93: 286: 24.00		PP2AB_HUMAN (8-312): 4.54e-178: 496: 46.73
+	Hs
		673059 CCND2_HUMAN (3-295): 1.61e-83: 254: 61.22		PP2AA_HUMAN (8-312): 1.1e-177: 495: 46.08