Protein: PO6F2
POU domain, class 6, transcription factor 2 (Retina-derived POU domain factor 1) (RPF-1)

Gene: PO6F2, POU6F2
Organism: Homo sapiens
Interactions: 152
UniProt ID: P78424

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154962

BHE40
Class E basic helix-loop-helix protein 40

2

1

High-throughput

0.783

High

163425

MEIS2
Homeobox protein Meis2

2

6

High-throughput

0.783

High

224968

TLX3
T-cell leukemia homeobox protein 3

2

20

High-throughput

0.783

High

226528

TLX2
T-cell leukemia homeobox protein 2

2

20

High-throughput

0.783

High

277090

PROP1
Homeobox protein prophet of Pit-1

2

20

High-throughput

0.783

High

330112

VENTX
Homeobox protein VENTX

2

20

High-throughput

0.783

High

351433

TBX6
T-box transcription factor TBX6

2

11

High-throughput

0.783

High

576210

PO2F1
POU domain, class 2, transcription factor 1

2

19

High-throughput

0.783

High

725037

HXC8
Homeobox protein Hox-C8

2

20

High-throughput

0.783

High

772142

MSX2
Homeobox protein MSX-2

2

20

High-throughput

0.783

High

942089

SOX10
Transcription factor SOX-10

2

20

High-throughput

0.783

High

1006886

NKX32
Homeobox protein Nkx-3.2

2

20

High-throughput

0.783

High

1007834

IRX4
Iroquois-class homeodomain protein IRX-4

2

7

High-throughput

0.783

High

1007908

HXC5
Homeobox protein Hox-C5

2

16

High-throughput

0.783

High

1007918

NFYC
Nuclear transcription factor Y subunit gamma

2

3

High-throughput

0.783

High

1007925

SIX1
Homeobox protein SIX1

2

13

High-throughput

0.783

High

1007927

ZFHX3
Zinc finger homeobox protein 3

2

11

High-throughput

0.783

High

1007931

ISX
Intestine-specific homeobox

2

20

High-throughput

0.783

High

1007998

VAX2
Ventral anterior homeobox 2

2

20

High-throughput

0.783

High

1008007

NGN3
Neurogenin-3

2

2

High-throughput

0.783

High

771579

HXD13
Homeobox protein Hox-D13

1

17

High-throughput

0.691

High

1007984

ZFHX2
Zinc finger homeobox protein 2

1

19

High-throughput

0.621

High

164561

TNPO2
Transportin-2

2

5

High-throughput

0.606

High

179039

IMA6
Importin subunit alpha-6

2

10

High-throughput

0.606

High

208823

ZBT24
Zinc finger and BTB domain-containing protein 24

2

1

High-throughput

0.606

High

253608

IMA7
Importin subunit alpha-7

2

10

High-throughput

0.606

High

262375

DTNB
Dystrobrevin beta

2

1

High-throughput

0.606

High

288295

GCM2
Chorion-specific transcription factor GCMb

2

1

High-throughput

0.606

High

296977

CCNK
Cyclin-K

2

4

High-throughput

0.606

High

552561

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

2

1

High-throughput

0.606

High

666820

CCNC
Cyclin-C

2

2

High-throughput

0.606

High

684193

DDX6
Probable ATP-dependent RNA helicase DDX6

2

1

High-throughput

0.606

High

761633

HSP74
Heat shock 70 kDa protein 4

2

6

High-throughput

0.606

High

775821

HNF1B
Hepatocyte nuclear factor 1-beta

2

20

High-throughput

0.606

High

842951

CDN2C
Cyclin-dependent kinase 4 inhibitor C

2

5

High-throughput

0.606

High

848959

MAGAC
Melanoma-associated antigen 12

2

4

High-throughput

0.606

High

853775

MK09
Mitogen-activated protein kinase 9

2

2

High-throughput

0.606

High

921035

FOSB
Protein FosB

2

12

High-throughput

0.606

High

931648

RD23B
UV excision repair protein RAD23 homolog B

2

3

High-throughput

0.606

High

936506

AF10
Protein AF-10

2

5

High-throughput

0.606

High

997633

CSK21
Casein kinase II subunit alpha

2

3

High-throughput

0.606

High

1007913

TP53B
TP53-binding protein 1

2

8

High-throughput

0.606

High

1007914

CAF1A
Chromatin assembly factor 1 subunit A

2

4

High-throughput

0.606

High

1007915

BFSP2
Phakinin

2

3

High-throughput

0.606

High

1007920

VEZF1
Vascular endothelial zinc finger 1

2

2

High-throughput

0.606

High

1007921

FHL2
Four and a half LIM domains protein 2

2

2

High-throughput

0.606

High

1007926

TCEA2
Transcription elongation factor A protein 2

2

2

High-throughput

0.606

High

1007928

PKN1
Serine/threonine-protein kinase N1

2

1

High-throughput

0.606

High

1007932

QRIC1
Transcriptional regulator QRICH1

2

7

High-throughput

0.606

High

1007939

ZFP1
Zinc finger protein 1 homolog

2

2

High-throughput

0.606

High

1007947

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

1

High-throughput

0.606

High

1007948

ZN410
Zinc finger protein 410

2

5

High-throughput

0.606

High

1007959

LMO3
LIM domain only protein 3

2

16

High-throughput

0.606

High

1007961

CCHCR
Coiled-coil alpha-helical rod protein 1

2

4

High-throughput

0.606

High

1007969

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.606

High

1007970

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

2

High-throughput

0.606

High

1007973

OPTN
Optineurin

2

4

High-throughput

0.606

High

1007975

ZFP91
E3 ubiquitin-protein ligase ZFP91

2

3

High-throughput

0.606

High

1007978

SMAD5
Mothers against decapentaplegic homolog 5

2

3

High-throughput

0.606

High

1007983

GLIS2
Zinc finger protein GLIS2

2

11

High-throughput

0.606

High

1007993

ZIM2
Zinc finger imprinted 2

2

4

High-throughput

0.606

High

1007996

COE1
Transcription factor COE1

2

1

High-throughput

0.606

High

1008000

GMEB2
Glucocorticoid modulatory element-binding protein 2

2

1

High-throughput

0.606

High

1008003

ZN148
Zinc finger protein 148

2

3

High-throughput

0.606

High

1008006

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

2

1

High-throughput

0.606

High

217078

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

750403

CSTF2
Cleavage stimulation factor subunit 2

2

0

High-throughput

0.580

High

1007916

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

2

0

High-throughput

0.580

High

1007919

CNCG
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

2

0

High-throughput

0.580

High

1007942

ZN574
Zinc finger protein 574

2

0

High-throughput

0.580

High

1007944

STRA8
Stimulated by retinoic acid gene 8 protein homolog

2

0

High-throughput

0.580

High

1007958

SMYD1
Histone-lysine N-methyltransferase SMYD1

2

0

High-throughput

0.580

High

1007971

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.580

High

1007982

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.580

High

1007990

THAP1
THAP domain-containing protein 1

2

0

High-throughput

0.580

High

1007991

AIRIM
AFG2-interacting ribosome maturation factor

2

0

High-throughput

0.580

High

1007994

ZBTB4
Zinc finger and BTB domain-containing protein 4

2

0

High-throughput

0.580

High

1007995

ZN319
Zinc finger protein 319

2

0

High-throughput

0.580

High

1008001

PADI4
Protein-arginine deiminase type-4

2

0

High-throughput

0.580

High

1008002

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.580

High

1008005

SSUH2
Protein SSUH2 homolog

2

0

High-throughput

0.580

High

1008008

NDK7
Nucleoside diphosphate kinase homolog 7

2

0

High-throughput

0.580

High

65031

GG6L9
Golgin subfamily A member 6-like protein 9

2

10

High-throughput

0.553

High

131400

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

2

High-throughput

0.553

High

169508

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

3

High-throughput

0.553

High

181789

EPHB6
Ephrin type-B receptor 6

2

4

High-throughput

0.553

High

213591

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

2

1

High-throughput

0.553

High

220896

XPOT
Exportin-T

2

1

High-throughput

0.553

High

644584

TENX
Tenascin-X

2

1

High-throughput

0.553

High

749896

KINH
Kinesin-1 heavy chain

2

3

High-throughput

0.553

High

1007910

LMNB2
Lamin-B2

2

8

High-throughput

0.553

High

1007912

ACTN3
Alpha-actinin-3

2

2

High-throughput

0.553

High

1007922

RBM39
RNA-binding protein 39

2

1

High-throughput

0.553

High

1007924

ARHG6
Rho guanine nucleotide exchange factor 6

2

1

High-throughput

0.553

High

1007930

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

7

High-throughput

0.553

High

1007936

TTC23
Tetratricopeptide repeat protein 23

2

1

High-throughput

0.553

High

1007937

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

1

High-throughput

0.553

High

1007954

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

7

High-throughput

0.553

High

1007960

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.553

High

1007965

ASB13
Ankyrin repeat and SOCS box protein 13

2

2

High-throughput

0.553

High

1007968

SORL
Sortilin-related receptor

2

1

High-throughput

0.553

High

1007977

STAC
SH3 and cysteine-rich domain-containing protein

2

19

High-throughput

0.553

High

1007986

N62CL
Nucleoporin-62 C-terminal-like protein

2

3

High-throughput

0.553

High

1007987

PARVG
Gamma-parvin

2

4

High-throughput

0.553

High

1007989

KLH11
Kelch-like protein 11

2

1

High-throughput

0.553

High

1007992

ANR10
Ankyrin repeat domain-containing protein 10

2

4

High-throughput

0.553

High

1007997

CTNA3
Catenin alpha-3

2

1

High-throughput

0.553

High

1007999

CDC23
Cell division cycle protein 23 homolog

2

2

High-throughput

0.553

High

60160

A2RRC6
ZFHX2 protein

1

1

High-throughput

0.515

High

1007972

Q96CP1
RELA protein

1

7

High-throughput

0.515

High

1007988

PLAT1
Phospholipase A and acyltransferase 1

1

0

High-throughput

0.493

High

139648

DLL1
Delta-like protein 1

1

1

High-throughput

0.489

High

586267

ZEP1
Zinc finger protein 40

1

6

High-throughput

0.481

High

1007911

TF65
Transcription factor p65

1

8

High-throughput

0.481

High

1007962

ZN384
Zinc finger protein 384

1

1

High-throughput

0.481

High

1007966

PIBF1
Progesterone-induced-blocking factor 1

1

3

High-throughput

0.481

High

1007967

TSC1
Hamartin

1

6

High-throughput

0.481

High

1007917

CUL3
Cullin-3

1

5

High-throughput

0.479

High

353240

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.470

High

1007906

PR20D
Proline-rich protein 20D

1

4

High-throughput

0.470

High

1007933

Q4G0R1
PIBF1 protein

1

3

High-throughput

0.470

High

1007940

Q6P4E2
LARP4 protein

1

2

High-throughput

0.470

High

1007945

TRI74
Tripartite motif-containing protein 74

1

6

High-throughput

0.470

High

1007949

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1007974

MY15B
Unconventional myosin-XVB

1

2

High-throughput

0.470

High

1007953

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.460

High

1007935

KLH22
Kelch-like protein 22

1

2

High-throughput

0.445

High

1007907

PR20A
Proline-rich protein 20A

1

4

High-throughput

0.439

High

1007943

LARP4
La-related protein 4

1

4

High-throughput

0.439

High

1007946

TRI73
Tripartite motif-containing protein 73

1

5

High-throughput

0.439

High

165847

OPLA
5-oxoprolinase

2

0

High-throughput

0.316

High

369971

CO5
Complement C5

2

0

High-throughput

0.316

High

1007909

MLRA
Myosin regulatory light chain 2, atrial isoform

2

0

High-throughput

0.316

High

1007923

MO4L2
Mortality factor 4-like protein 2

2

0

High-throughput

0.316

High

1007929

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.316

High

1007934

FND3B
Fibronectin type III domain-containing protein 3B

2

0

High-throughput

0.316

High

1007938

UFSP1
Ufm1-specific protease 1

2

0

High-throughput

0.316

High

1007941

THADA
tRNA

2

0

High-throughput

0.316

High

1007950

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

1007951

MSRB3
Methionine-R-sulfoxide reductase B3

2

0

High-throughput

0.316

High

1007952

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.316

High

1007955

BANP
Protein BANP

2

0

High-throughput

0.316

High

1007956

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.316

High

1007957

KDF1
Keratinocyte differentiation factor 1

2

0

High-throughput

0.316

High

1007963

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.316

High

1007964

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.316

High

1007976

CIB3
Calcium and integrin-binding family member 3

2

0

High-throughput

0.316

High

1007979

MIEN1
Migration and invasion enhancer 1

2

0

High-throughput

0.316

High

1007980

UBAC1
Ubiquitin-associated domain-containing protein 1

2

0

High-throughput

0.316

High

1007981

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.316

High

1007985

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1008004

VP9D1
VPS9 domain-containing protein 1

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025