HitPredict

Interactor 1: RV161 (P25343)
Reduced viability upon starvation protein 161
Gene: RVS161

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	10992286, 15561700, 21035341
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization GO:0030479 - actin cortical patch GO:0043332 - mating projection tip GO:0051666 - actin cortical patch localization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 265 Sc			1 633
+	Sc
		764174 RV167_YEAST (1-260): 7.78e-70: 224: 25.27		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Hs
		126939 DNMBP_HUMAN (4-258): 3.1e-69: 233: 15.18		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Hs
		126878 BIN1_HUMAN (3-230): 3.22e-65: 215: 19.16		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Mm
		139043 BIN1_MOUSE (3-230): 7.65e-63: 208: 19.16		WASL_MOUSE (3-154): 6.45e-45: 169: 28.95
+	Dm
		1180683 Q7KLE5_DROME (1-236): 4.2e-65: 215: 21.25		Q9VAT0_DROME (3-215): 8.21e-40: 154: 18.18
+	Rn
		139978 AMPH_RAT (3-241): 9.38e-72: 234: 22.86		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Hs
		203213 AMPH_HUMAN (3-241): 6.5e-70: 229: 22.86		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Rn
		139991 BIN1_RAT (3-230): 1.14e-62: 208: 19.16		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Hs
		827768 AMPH_HUMAN (3-241): 6.5e-70: 229: 22.86		CABIN_HUMAN (128-579): 2.58e-19: 95.2: 17.99
+	Sp
		193724 HOB1_SCHPO (1-260): 3.47e-66: 214: 24.19		WSP1_SCHPO (4-416): 3.99e-22: 102: 22.03