HitPredict

Interactor 1: RRP43 (P25359)
Exosome complex component RRP43 (Ribosomal RNA-processing protein 43)
Gene: RRP43

Interactor 2: RRP41 (P46948)
Exosome complex component SKI6 (Extracellular mutant protein 20) (Ribosomal RNA-processing protein 41) (Superkiller protein 6)
Gene: SKI6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 11805826, 17173052, 16554755, 16429126, 31662437, 37968396, 18314965, 19707589, 16729021
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RNase_PH, RNase_PH~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
and 9 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 394
Sc

1 246
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024