HitPredict

Interactor 1: OCA4 (P25366)
Protein OCA4 (Oxidant-induced cell-cycle arrest protein 4)
Gene: OCA4

Interactor 2: SIW14 (P53965)
Inositol phosphatase SIW14 (EC 3.6.1.52) (5-PP-InsP phosphatase) (Inositol pyrophosphate phosphatase SIW14) (Oxidant-induced cell-cycle arrest protein 3) (Synthetic interaction with WHI2 protein 14)
Gene: SIW14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Y_phosphatase2~Y_phosphatase2
Common GO terms	GO:0005737 - cytoplasm GO:0016791 - phosphatase activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 362 Sc			1 281
+	Sc
		630378 OCA4_YEAST (1-362): 0: 538: 100.00		OCA1_YEAST (108-277): 1.35e-75: 232: 32.96
+	Sc
		630380 OCA4_YEAST (1-362): 0: 538: 100.00		OCA2_YEAST (117-266): 9.91e-63: 197: 36.77
+	Sc
		630385 OCA4_YEAST (1-362): 0: 538: 100.00		OCA6_YEAST (116-281): 3.93e-53: 174: 23.91
+	At
		1195865 DSP2_ARATH (2-207): 4.3e-68: 216: 23.22		DSP2_ARATH (115-269): 5.9e-77: 236: 43.92
+	Sc
		842770 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA1_YEAST (108-277): 1.35e-75: 232: 32.96
+	Sc
		842773 OCA6_YEAST (2-209): 2.17e-42: 148: 19.54		OCA1_YEAST (108-277): 1.35e-75: 232: 32.96
+	Sc
		842769 OCA2_YEAST (3-205): 2.3e-39: 140: 18.75		OCA1_YEAST (108-277): 1.35e-75: 232: 32.96
+	Sc
		866674 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA2_YEAST (117-266): 9.91e-63: 197: 36.77
+	Sc
		866676 OCA6_YEAST (2-209): 2.17e-42: 148: 19.54		OCA2_YEAST (117-266): 9.91e-63: 197: 36.77
+	Sc
		866755 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA6_YEAST (116-281): 3.93e-53: 174: 23.91