HitPredict

Interactor 1: NFS1 (P25374)
Cysteine desulfurase, mitochondrial (EC 2.8.1.7) (tRNA-splicing protein SPL1)
Gene: NFS1

Interactor 2: ISU1 (Q03020)
Iron sulfur cluster assembly protein 1, mitochondrial (Iron sulfur cluster scaffold protein 1)
Gene: ISU1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 11805837, 23946486, 29386296, 19491103, 24573684, 28941588, 37968396, 12947415, 16341089
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_5~NifU_N
Common GO terms GO:0002098 - tRNA wobble uridine modification
GO:0005739 - mitochondrion
GO:0006879 - intracellular iron ion homeostasis
GO:0016226 - iron-sulfur cluster assembly
GO:1990229 - iron-sulfur cluster assembly complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 497
Sc

1 165
+ Sc
+ Hs
+ Ec
+ Ec
+ Cj
+ Nv
+ Bs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024