HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 801 Hs			1 293
+	Hs
		1067122 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		244894 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		243851 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		244920 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CSTFT_HUMAN (46-229): 2.35e-38: 144: 19.60
+	Hs
		244009 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CSTF2_HUMAN (46-218): 6.49e-36: 137: 18.62
+	Hs
		245064 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		244481 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Hs
		998651 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516480 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1316894 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Sc
		866254 GCN5_YEAST (275-456): 2.99e-40: 155: 26.63		NOP15_YEAST (14-185): 3.16e-37: 133: 30.64
+	Sp
		252623 YK82_SCHPO (27-186): 5.63e-31: 132: 29.88		YQL5_SCHPO (23-192): 2.84e-44: 153: 36.93
+	Hs
		999182 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		516706 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1342822 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Rn
		78192 Q6AYL3_RAT (323-598): 1.86e-35: 139: 24.28		ELAV1_RAT (26-127): 1.55e-25: 105: 20.59
+	Hs
		1342856 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		RBMX2_HUMAN (14-235): 3.77e-30: 117: 17.54
+	Hs
		1073643 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92