Interactor 1: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Interactor 2: CASPA (Q92851)
Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
Gene: CASP10

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.666

The method score is based on:

Property Details
Experiments 15659383, 9045686, 9325248, 11717445
Identification Methods biochemical, affinity chromatography technology, coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0031265 - CD95 death-inducing signaling complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 335
Hs

1 521
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024