HitPredict - High confidence protein-protein interactions

Interactor 1: RPAB3 (P20436)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (ABC14.4) (ABC14.5) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide)
Gene: RPB8

Interactor 2: RPAB4 (P40422)
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha)
Gene: RPC10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	37968396, 25315781, 19394294, 21048197
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001172 - RNA-templated transcription GO:0003677 - DNA binding GO:0003899 - DNA-directed RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 16 others more... GO:0005665 - RNA polymerase II, core complex GO:0005666 - RNA polymerase III complex GO:0005736 - RNA polymerase I complex GO:0006360 - transcription by RNA polymerase I GO:0006361 - transcription initiation at RNA polymerase I promoter GO:0006362 - transcription elongation by RNA polymerase I GO:0006363 - termination of RNA polymerase I transcription GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0006368 - transcription elongation by RNA polymerase II GO:0006383 - transcription by RNA polymerase III GO:0006384 - transcription initiation at RNA polymerase III promoter GO:0006386 - termination of RNA polymerase III transcription GO:0042254 - ribosome biogenesis GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I GO:0042797 - tRNA transcription by RNA polymerase III
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	146
Sc

1	70

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Last updated: 11Aug2025