HitPredict

Interactor 1: MX1 (P20591)
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Gene: MX1

Interactor 2: TRPC7 (Q9HCX4)
Short transient receptor potential channel 7 (TrpC7) (Transient receptor protein 7) (TRP-7) (hTRP7)
Gene: TRPC7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15757897
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 862
+	Hs
		633403 MX1_HUMAN (1-662): 0: 694: 100.00		TRPC6_HUMAN (47-853): 0: 607: 74.37
+	Hs
		633374 MX1_HUMAN (1-662): 0: 694: 100.00		TRPC3_HUMAN (19-857): 0: 605: 80.64
+	Rn
		638962 DYN1_RAT (46-561): 0: 606: 31.09		Q99N78_RAT (47-855): 0: 598: 73.95
+	Hs
		633401 MX1_HUMAN (1-662): 0: 694: 100.00		TRPC5_HUMAN (44-829): 2.39e-163: 502: 37.52
+	Hs
		633397 MX1_HUMAN (1-662): 0: 694: 100.00		TRPC4_HUMAN (44-824): 1.26e-157: 487: 37.89
+	Hs
		633360 MX1_HUMAN (1-662): 0: 694: 100.00		TRPC1_HUMAN (30-827): 6.93e-140: 436: 32.81
+	Rn
		638961 DYN1_RAT (46-561): 0: 606: 31.09		Q8VD38_RAT (44-829): 3.86e-165: 507: 37.64