HitPredict

Interactor 1: S100P (P25815)
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)
Gene: S100P

Interactor 2: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000287 - magnesium ion binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 735
+	Hs
		615217 S10A1_HUMAN (2-93): 1.61e-35: 117: 53.26		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		642947 S10A4_HUMAN (3-95): 3.19e-33: 112: 41.94		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		661265 S10A2_HUMAN (2-95): 5.21e-32: 109: 40.43		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		380782 S100B_HUMAN (1-92): 1.7e-31: 107: 50.00		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		416623 S10A6_HUMAN (3-91): 5.01e-26: 93.8: 34.83		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		682050 CRNN_HUMAN (1-94): 2.31e-32: 118: 35.11		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92
+	Hs
		707403 S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97		AKT3_HUMAN (358-719): 9.26e-123: 377: 21.87
+	Hs
		681685 S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92
+	Hs
		380732 S100B_HUMAN (1-92): 1.7e-31: 107: 50.00		KAPCA_HUMAN (414-712): 3.66e-114: 350: 29.71
+	Hs
		682028 S10AE_HUMAN (2-83): 9.09e-21: 80.7: 25.61		AKT1_HUMAN (411-724): 3.69e-122: 375: 25.92