HitPredict

Interactor 1: RSC6 (P25632)
Chromatin structure-remodeling complex protein RSC6 (Remodel the structure of chromatin complex subunit 6)
Gene: RSC6

Interactor 2: RSC1 (P53236)
Chromatin structure-remodeling complex subunit RSC1 (RSC complex subunit RSC1) (Remodel the structure of chromatin complex subunit 1)
Gene: RSC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	16429126, 37968396, 10619019, 32496195, 22359657
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006337 - nucleosome disassembly GO:0006338 - chromatin remodeling GO:0016514 - SWI/SNF complex GO:0016586 - RSC-type complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Sc			1 928
+	Sc
		635535 RSC6_YEAST (1-483): 0: 555: 100.00		RSC2_YEAST (8-816): 0: 578: 46.49
+	Hs
		1067082 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51
+	Hs
		1067090 SMRD1_HUMAN (9-464): 3.68e-149: 437: 17.06		BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51
+	Sc
		635500 RSC6_YEAST (1-483): 0: 555: 100.00		BDF1_YEAST (187-532): 2.06e-18: 92.4: 11.54
+	Sc
		635493 RSC6_YEAST (1-483): 0: 555: 100.00		STH1_YEAST (235-344): 5.88e-11: 68.7: 24.55
+	Sc
		635522 RSC6_YEAST (1-483): 0: 555: 100.00		RSC4_YEAST (26-120): 9.35e-11: 67.5: 26.80
+	Sc
		635526 RSC6_YEAST (1-483): 0: 555: 100.00		GCN5_YEAST (35-109): 1.3e-10: 66.7: 35.07
+	Mm
		1111961 SMRD2_MOUSE (1-464): 2.74e-152: 445: 17.13		SMCA4_MOUSE (3-107): 5.13e-30: 130: 33.65
+	Hs
		847046 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		SMCA4_HUMAN (3-107): 1.76e-28: 126: 33.33
+	Hs
		631539 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		BRD2_HUMAN (3-234): 1.91e-28: 124: 13.47
+	Hs
		1272989 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		BRD7_HUMAN (3-227): 2.34e-27: 120: 12.34
+	Hs
		847055 SMRD1_HUMAN (9-464): 3.68e-149: 437: 17.06		SMCA4_HUMAN (3-107): 1.76e-28: 126: 33.33
+	Hs
		846840 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		SMCA2_HUMAN (3-107): 1.23e-26: 119: 28.00
+	Hs
		631547 SMRD1_HUMAN (9-464): 3.68e-149: 437: 17.06		BRD2_HUMAN (3-234): 1.91e-28: 124: 13.47
+	Hs
		846849 SMRD1_HUMAN (9-464): 3.68e-149: 437: 17.06		SMCA2_HUMAN (3-107): 1.23e-26: 119: 28.00
+	Hs
		244743 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		BRD4_HUMAN (3-160): 3.4e-24: 112: 18.52
+	Hs
		244782 SMRD1_HUMAN (9-464): 3.68e-149: 437: 17.06		BRD4_HUMAN (3-160): 3.4e-24: 112: 18.52
+	Hs
		1199177 SMRD2_HUMAN (1-464): 3.83e-151: 443: 17.13		PB1_HUMAN (190-723): 8.96e-20: 97.8: 14.31
+	Sc
		603331 SNF12_YEAST (5-483): 1.52e-151: 445: 27.63		SNF2_YEAST (11-108): 7.23e-18: 91.4: 31.00
+	Sc
		863666 SNF12_YEAST (5-483): 1.52e-151: 445: 27.63		GCN5_YEAST (35-109): 1.3e-10: 66.7: 35.07