HitPredict

Interactor 1: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Interactor 2: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031398 - positive regulation of protein ubiquitination GO:0043130 - ubiquitin binding and 2 others more... GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0051087 - protein-folding chaperone binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	324
Hs

1	618

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024