Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 35271311, 14733938, 20980621, 24121268, 33961781, 19193609, 15887188, 12376572
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 234
Hs

1 263
+ Sp
+ Hs
+ At
+ Hs
+ Hs
+ Ce
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Mt
+ Ph
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024