Protein: MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog)

Gene: MTU1, TRMU
Organism: Homo sapiens
Interactions: 86
UniProt ID: O75648

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002143 - tRNA wobble position uridine thiolation
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0061708 - tRNA-5-taurinomethyluridine 2-sulfurtransferase

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

272328

CH60
60 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.628

High

272384

THUM3
tRNA

2

0

High-throughput

0.602

High

226070

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

272329

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

272333

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

1

High-throughput

0.536

High

272335

HS71L
Heat shock 70 kDa protein 1-like

1

2

High-throughput

0.536

High

272344

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

272379

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

1

High-throughput

0.536

High

272388

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.536

High

118137

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.513

High

157268

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.513

High

272331

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.513

High

272337

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.513

High

272339

CACP
Carnitine O-acetyltransferase

1

0

High-throughput

0.513

High

272342

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.513

High

272343

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

272347

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.513

High

272348

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

High-throughput

0.513

High

272349

PEX6
Peroxisomal ATPase PEX6

1

0

High-throughput

0.513

High

272350

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

272359

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.513

High

272361

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

272368

FCSK
L-fucose kinase

1

0

High-throughput

0.513

High

272370

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

1

0

High-throughput

0.513

High

272376

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.513

High

272377

SYNM
Asparaginyl-tRNA synthetase

1

0

High-throughput

0.513

High

272378

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.513

High

272385

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

272392

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

272394

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

272395

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.513

High

272399

SARDH
Sarcosine dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

272400

RUVB1
RuvB-like 1

1

0

High-throughput

0.513

High

272401

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.513

High

272365

TBA1A
Tubulin alpha-1A chain

1

2

High-throughput

0.489

High

272381

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.489

High

272324

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

272338

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.426

High

272357

F219B
Protein FAM219B

3

0

High-throughput

0.347

High

272332

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.328

High

272345

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.328

High

272397

HXC10
Homeobox protein Hox-C10

2

0

High-throughput

0.328

High

47914

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.279

Low

231265

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.279

Low

272325

TBB5
Tubulin beta chain

1

0

High-throughput

0.279

Low

272327

RAP2A
Ras-related protein Rap-2a

1

0

High-throughput

0.279

Low

272330

MBL2
Mannose-binding protein C

1

0

High-throughput

0.279

Low

272334

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.279

Low

272340

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

0

High-throughput

0.279

Low

272341

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

272346

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

High-throughput

0.279

Low

272351

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

0

High-throughput

0.279

Low

272352

CART

1

0

High-throughput

0.279

Low

272353

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.279

Low

272354

PSMG4
Proteasome assembly chaperone 4

1

0

High-throughput

0.279

Low

272355

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.279

Low

272356

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.279

Low

272358

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

272360

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.279

Low

272362

WDR59
GATOR2 complex protein WDR59

1

0

High-throughput

0.279

Low

272363

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.279

Low

272366

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.279

Low

272367

CEP97
Centrosomal protein of 97 kDa

1

0

High-throughput

0.279

Low

272369

WDTC1
WD and tetratricopeptide repeats protein 1

1

0

High-throughput

0.279

Low

272371

FAT3
Protocadherin Fat 3

1

0

High-throughput

0.279

Low

272372

STYX
Serine/threonine/tyrosine-interacting protein

1

0

High-throughput

0.279

Low

272373

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.279

Low

272374

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.279

Low

272375

NSUN4
5-methylcytosine rRNA methyltransferase NSUN4

1

0

High-throughput

0.279

Low

272380

IF140
Intraflagellar transport protein 140 homolog

1

0

High-throughput

0.279

Low

272382

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.279

Low

272386

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

272387

PIP30
PSME3-interacting protein

1

0

High-throughput

0.279

Low

272389

SMOC1
SPARC-related modular calcium-binding protein 1

1

0

High-throughput

0.279

Low

272391

ESRP2
Epithelial splicing regulatory protein 2

1

0

High-throughput

0.279

Low

272393

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.279

Low

272396

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.279

Low

272398

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.279

Low

272402

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

272403

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.279

Low

172721

ZN185
Zinc finger protein 185

1

0

High-throughput

0.269

Low

272326

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

272336

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

272364

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

272390

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

272383

MTA3
Metastasis-associated protein MTA3

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024