HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27114451, 19193609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Hs			1 399
+	Hs
		656249 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		893686 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		637721 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		656280 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		893715 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Zm
		59016 A3FMB9_MAIZE (4-230): 4.78e-91: 269: 41.30		K7UR93_MAIZE (5-384): 2.9e-111: 333: 35.25
+	Hs
		637757 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		656337 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		637749 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656327 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656323 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Dm
		1278653 PSA5_DROME (1-234): 3.08e-97: 285: 33.88		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		893771 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		893768 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		893761 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		637656 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		656183 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		872130 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		637369 PSA1_HUMAN (1-233): 1.31e-89: 266: 30.67		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		893645 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06