HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: TAL2 (Q16559)
T-cell acute lymphocytic leukemia protein 2 (TAL-2) (Class A basic helix-loop-helix protein 19) (bHLHa19)
Gene: TAL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.80	0.665

Property	Details
Experiments	7957052, 20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 108
+	Hs
		638508 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		TAL2_HUMAN (1-108): 1.96e-36: 121: 100.00
+	Mm
		1143746 LMO3_MOUSE (30-156): 5.7e-39: 130: 58.27		TAL2_MOUSE (1-108): 2.09e-35: 118: 86.11
+	Mm
		1143747 RBTN1_MOUSE (11-150): 3.96e-38: 128: 52.86		TAL2_MOUSE (1-108): 2.09e-35: 118: 86.11
+	Mm
		603898 RBTN2_MOUSE (1-158): 3.35e-41: 137: 99.37		TAL1_MOUSE (1-104): 5.01e-27: 102: 47.37
+	Mm
		604035 LMO3_MOUSE (30-156): 5.7e-39: 130: 58.27		TAL1_MOUSE (1-104): 5.01e-27: 102: 47.37
+	Hs
		524537 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		LYL1_HUMAN (1-108): 4.26e-24: 94.3: 47.22
+	Hs
		568179 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		TAL1_HUMAN (1-104): 8.18e-24: 94.3: 53.21
+	Hs
		524538 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		LYL1_HUMAN (1-108): 4.26e-24: 94.3: 47.22
+	Hs
		568180 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		TAL1_HUMAN (1-104): 8.18e-24: 94.3: 53.21
+	Hs
		638265 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		HEN1_HUMAN (4-58): 6.58e-22: 85: 60.00
+	Dm
		114761 M9PD53_DROME (2-86): 7.78e-15: 72.3: 17.44		Q9VHG3_DROME (4-90): 1.41e-24: 95.4: 32.96
+	Dm
		80870 APTE_DROME (94-155): 2.27e-11: 62.3: 20.97		DIMM_DROME (3-108): 2.11e-25: 99.2: 31.48
+	Dm
		1368265 Q9VJ00_DROME (2-86): 1.05e-14: 71.9: 17.44		Q9W4I4_DROME (4-59): 9.81e-22: 85.4: 55.36
+	Dm
		1359764 Q9V472_DROME (94-155): 1.72e-09: 56.9: 22.58		Q9VHG3_DROME (4-90): 1.41e-24: 95.4: 32.96
+	Dm
		112565 M9NCY1_DROME (2-86): 7.53e-12: 63.8: 17.44		Q9W4I4_DROME (4-59): 9.81e-22: 85.4: 55.36