HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: IKZF3 (Q9UKT9)
Zinc finger protein Aiolos (Ikaros family zinc finger protein 3)
Gene: IKZF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 509
+	Hs
		846679 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		ZNF84_HUMAN (2-405): 5.8e-155: 460: 14.85
+	Hs
		638487 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		ZNF84_HUMAN (2-405): 5.8e-155: 460: 14.85
+	Hs
		638281 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		IKZF1_HUMAN (31-505): 1.69e-140: 416: 55.51
+	Hs
		903710 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		IKZF1_HUMAN (31-505): 1.69e-140: 416: 55.51
+	Hs
		1033682 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		IKZF1_HUMAN (31-505): 1.69e-140: 416: 55.51
+	Hs
		638501 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		IKZF1_HUMAN (31-505): 1.69e-140: 416: 55.51
+	Hs
		903791 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		IKZF3_HUMAN (1-509): 2.04e-134: 400: 100.00
+	Hs
		638592 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		IKZF3_HUMAN (1-509): 2.04e-134: 400: 100.00
+	Hs
		855972 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		ZN135_HUMAN (184-509): 7.16e-124: 378: 12.50
+	Hs
		1033698 LHX4_HUMAN (89-155): 5.05e-11: 61.5: 26.87		IKZF1_HUMAN (31-505): 1.69e-140: 416: 55.51
+	Hs
		563363 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		ZNF19_HUMAN (76-283): 1.64e-66: 223: 24.77
+	Hs
		563364 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		ZNF19_HUMAN (76-283): 1.64e-66: 223: 24.77
+	Hs
		1078405 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		ZKSC8_HUMAN (40-276): 2.8e-64: 220: 22.36
+	Hs
		1332089 PDLI7_HUMAN (3-83): 1.76e-15: 74.2: 25.61		IKZF5_HUMAN (111-504): 4.95e-87: 275: 23.62
+	Hs
		1332093 LHX3_HUMAN (92-155): 2.6e-12: 65: 23.44		IKZF5_HUMAN (111-504): 4.95e-87: 275: 23.62
+	Hs
		903756 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		ZN397_HUMAN (4-276): 7.84e-60: 207: 22.97
+	Hs
		903785 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		RBAK_HUMAN (225-509): 9.75e-33: 134: 10.30
+	Hs
		638344 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		ZNF34_HUMAN (144-485): 1.46e-21: 99.8: 15.05
+	Dm
		592803 Q9VTW5_DROME (9-154): 2.94e-42: 150: 31.97		CF2_DROME (134-220): 3.23e-09: 61.2: 31.92
+	Dm
		114398 M9PCA3_DROME (9-154): 8.59e-41: 145: 32.65		CF2_DROME (134-220): 3.23e-09: 61.2: 31.92