Protein: P2RY2
P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor)

Gene: P2RY2
Organism: Homo sapiens
Interactions: 106
UniProt ID: P41231

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006873 - intracellular monoatomic ion homeostasis
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0031686 - A1 adenosine receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833889

DJC16
DnaJ homolog subfamily C member 16

1

8

High-throughput

0.618

High

184137

RER1
Protein RER1

1

3

High-throughput

0.536

High

184402

SURF4
Surfeit locus protein 4

1

1

High-throughput

0.536

High

256000

S19A2
Thiamine transporter 1

1

8

High-throughput

0.536

High

270625

ATP9A
Probable phospholipid-transporting ATPase IIA

1

11

High-throughput

0.536

High

354094

CLPT1
Putative lipid scramblase CLPTM1

1

9

High-throughput

0.536

High

419966

B3A2
Anion exchange protein 2

1

6

High-throughput

0.536

High

565571

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

627277

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

20

High-throughput

0.536

High

661234

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

20

High-throughput

0.536

High

833810

AGRE5
Adhesion G protein-coupled receptor E5

1

12

High-throughput

0.536

High

833811

CAV2
Caveolin-2

1

7

High-throughput

0.536

High

833812

AT12A
Potassium-transporting ATPase alpha chain 2

1

20

High-throughput

0.536

High

833816

CLN3
Battenin

1

1

High-throughput

0.536

High

833817

S39A6
Zinc transporter ZIP6

1

20

High-throughput

0.536

High

833819

S39AE
Metal cation symporter ZIP14

1

20

High-throughput

0.536

High

833822

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

20

High-throughput

0.536

High

833826

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

2

High-throughput

0.536

High

833829

S39A4
Zinc transporter ZIP4

1

20

High-throughput

0.536

High

833838

TM87A
Transmembrane protein 87A

1

8

High-throughput

0.536

High

833841

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

12

High-throughput

0.536

High

833844

LMBR1
Limb region 1 protein homolog

1

3

High-throughput

0.536

High

833846

YLAT2
Y+L amino acid transporter 2

1

12

High-throughput

0.536

High

833858

S29A1
Equilibrative nucleoside transporter 1

1

3

High-throughput

0.536

High

833859

RNF5
E3 ubiquitin-protein ligase RNF5

1

9

High-throughput

0.536

High

833861

DERL1
Derlin-1

1

6

High-throughput

0.536

High

833863

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

2

High-throughput

0.536

High

833866

TTYH3
Protein tweety homolog 3

1

6

High-throughput

0.536

High

833870

PIGU
GPI-anchor transamidase component PIGU

1

4

High-throughput

0.536

High

833882

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

4

High-throughput

0.536

High

833885

S39AA
Zinc transporter ZIP10

1

20

High-throughput

0.536

High

403140

APOB
Apolipoprotein B-100

1

0

High-throughput

0.513

High

421645

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

165540

SCAM3
Secretory carrier-associated membrane protein 3

1

7

High-throughput

0.489

High

178916

SCAM2
Secretory carrier-associated membrane protein 2

1

7

High-throughput

0.489

High

189122

IPO8
Importin-8

1

20

High-throughput

0.489

High

212556

GPAA1
GPI-anchor transamidase component GPAA1

1

1

High-throughput

0.489

High

246279

MARH6
E3 ubiquitin-protein ligase MARCHF6

1

1

High-throughput

0.489

High

399665

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

8

High-throughput

0.489

High

664950

ERD21
ER lumen protein-retaining receptor 1

1

8

High-throughput

0.489

High

833813

SYJ2B
Synaptojanin-2-binding protein

1

20

High-throughput

0.489

High

833814

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

2

High-throughput

0.489

High

833815

STX5
Syntaxin-5

1

1

High-throughput

0.489

High

833820

NOMO1
BOS complex subunit NOMO1

1

4

High-throughput

0.489

High

833821

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.489

High

833823

MBRL
Membralin

1

4

High-throughput

0.489

High

833824

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

1

12

High-throughput

0.489

High

833825

RABL3
Rab-like protein 3

1

7

High-throughput

0.489

High

833827

RINT1
RAD50-interacting protein 1

1

8

High-throughput

0.489

High

833828

ZNT6
Zinc transporter 6

1

12

High-throughput

0.489

High

833830

THADA
tRNA

1

7

High-throughput

0.489

High

833831

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

2

High-throughput

0.489

High

833832

DYM
Dymeclin

1

9

High-throughput

0.489

High

833833

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

6

High-throughput

0.489

High

833834

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

5

High-throughput

0.489

High

833835

K2013
Uncharacterized protein KIAA2013

1

9

High-throughput

0.489

High

833836

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

6

High-throughput

0.489

High

833837

INT1
Integrator complex subunit 1

1

9

High-throughput

0.489

High

833839

MCU
Calcium uniporter protein, mitochondrial

1

3

High-throughput

0.489

High

833840

ZNT7
Zinc transporter 7

1

12

High-throughput

0.489

High

833842

GOGA5
Golgin subfamily A member 5

1

7

High-throughput

0.489

High

833845

BRI3B
BRI3-binding protein

1

1

High-throughput

0.489

High

833847

TM9S4
Transmembrane 9 superfamily member 4

1

14

High-throughput

0.489

High

833848

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.489

High

833849

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

833850

YIPF5
Protein YIPF5

1

6

High-throughput

0.489

High

833852

INT12
Integrator complex subunit 12

1

5

High-throughput

0.489

High

833853

YIPF6
Protein YIPF6

1

6

High-throughput

0.489

High

833854

SAAL1
Protein SAAL1

1

3

High-throughput

0.489

High

833855

RN185
E3 ubiquitin-protein ligase RNF185

1

9

High-throughput

0.489

High

833856

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

10

High-throughput

0.489

High

833860

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

3

High-throughput

0.489

High

833862

PTSS2
Phosphatidylserine synthase 2

1

10

High-throughput

0.489

High

833864

FACD2
Fanconi anemia group D2 protein

1

10

High-throughput

0.489

High

833865

XPO4
Exportin-4

1

20

High-throughput

0.489

High

833867

DERL2
Derlin-2

1

6

High-throughput

0.489

High

833868

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.489

High

833869

GHITM
Growth hormone-inducible transmembrane protein

1

4

High-throughput

0.489

High

833871

HEAT1
HEAT repeat-containing protein 1

1

6

High-throughput

0.489

High

833872

AT133
Polyamine-transporting ATPase 13A3

1

20

High-throughput

0.489

High

833873

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

2

High-throughput

0.489

High

833874

TM9S3
Transmembrane 9 superfamily member 3

1

14

High-throughput

0.489

High

833875

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.489

High

833876

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

7

High-throughput

0.489

High

833877

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

5

High-throughput

0.489

High

833878

DJC11
DnaJ homolog subfamily C member 11

1

7

High-throughput

0.489

High

833879

RMND1
Required for meiotic nuclear division protein 1 homolog

1

2

High-throughput

0.489

High

833880

TM160
Transmembrane protein 160

1

1

High-throughput

0.489

High

833881

T161A
Transmembrane protein 161A

1

6

High-throughput

0.489

High

833883

FA8A1
Protein FAM8A1

1

1

High-throughput

0.489

High

833884

ATIF1
ATPase inhibitor, mitochondrial

1

2

High-throughput

0.489

High

833886

TPC1
Two pore channel protein 1

1

4

High-throughput

0.489

High

833887

TMCO1
Calcium load-activated calcium channel

1

6

High-throughput

0.489

High

833888

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

4

High-throughput

0.489

High

833891

TNPO3
Transportin-3

1

20

High-throughput

0.489

High

557150

SRC
Proto-oncogene tyrosine-protein kinase Src

1

11

Small-scale

0.479

High

749755

CADH5
Cadherin-5

1

3

Small-scale

0.479

High

162800

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

Small-scale

0.457

High

833857

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

8

Small-scale

0.437

High

322009

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.279

Low

331842

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.279

Low

690699

AOFB
Amine oxidase [flavin-containing] B

1

0

High-throughput

0.279

Low

833818

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.279

Low

833851

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.279

Low

833890

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.279

Low

833843

BRK1
Protein BRICK1

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025