Interactor 1: NFKB1 (P25799)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: NFKB1 (P25799)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.887

The method score is based on:

Property Details
Experiments 23538752, 19531803, 18586011, 9556555
Identification Methods pull down, electrophoretic mobility supershift assay, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ank~Ank_2, Ank~RHD_dimer, Ank_2~Ank_2, Ank_2~RHD_dimer, Death~Death, RHD_dimer~RHD_dimer, RHD_DNA_bind~RHD_dimer, RHD_DNA_bind~RHD_DNA_bind
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
and 66 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 971
Mm

1 971
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Last updated: 15 Jul 2024