Interactor 1: NFKB1 (P25799)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: NOS2 (P29477)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 12595462, 19662631, 19556165, 18586011, 12138131, 17041221
Identification Methods electrophoretic mobility supershift assay, anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0071222 - cellular response to lipopolysaccharide
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 971
Mm

1 1144
+ Rn
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024