HitPredict

Interactor 1: NFKB1 (P25799)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: IKBA (Q9Z1E3)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha)
Gene: Nfkbia

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 21098220, 16928772, 21343618
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank~Ank_5, Ank_2~Ank_2, Ank_2~Ank_5, Ank_2~RHD_dimer
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
GO:0031072 - heat shock protein binding
and 10 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 971
Mm

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Last updated: 15 Jul 2024