Interactor 1: AGT1 (P21549)
Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase) (SPT) (EC 2.6.1.51)
Gene: AGXT
Interactor 2: AGT1 (P21549)
Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase) (SPT) (EC 2.6.1.51)
Gene: AGXT
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.80 | 1.00 | 0.897 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 22529745, 12899834, unassigned1304 |
| Identification Methods | two hybrid, static light scattering, molecular sieving, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_5~Aminotran_5 |
| Common GO terms | GO:0004760 - L-serine-pyruvate transaminase activity GO:0005777 - peroxisome GO:0005782 - peroxisomal matrix GO:0005829 - cytosol GO:0006563 - L-serine metabolic process and 13 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
