Protein: SAM50
Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3)

Gene: SAM50, SAMM50
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q9Y512

Gene Ontology (top 5):
GO:0001401 - SAM complex
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0007007 - inner mitochondrial membrane organization
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

264659

MTX2
Metaxin-2

5

3

Small-scale

0.935

High

1037169

MTX1
Metaxin-1

2

4

Small-scale

0.806

High

1347838

MIC19
MICOS complex subunit MIC19

6

1

Small-scale

0.740

High

1136859

FAXC
Failed axon connections homolog

1

3

High-throughput

0.691

High

1088710

MIC60
MICOS complex subunit MIC60

4

1

Small-scale

0.689

High

1310416

MIC25
MICOS complex subunit MIC25

3

1

High-throughput

0.653

High

128678

DNM1L
Dynamin-1-like protein

2

1

Small-scale

0.624

High

1166802

MIC27
MICOS complex subunit MIC27

2

1

High-throughput

0.611

High

1346567

DJC11
DnaJ homolog subfamily C member 11

2

3

High-throughput

0.611

High

330750

TOM40
Mitochondrial import receptor subunit TOM40 homolog

2

2

Small-scale

0.595

High

325474

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

2

High-throughput

0.588

High

229172

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

304897

MFN2
Mitofusin-2

2

1

Small-scale

0.584

High

601422

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

Small-scale

0.561

High

1037032

SQSTM
Sequestosome-1

1

2

Small-scale

0.561

High

525680

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

1315559

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

0

Small-scale

0.559

High

1326923

MFF
Mitochondrial fission factor

2

0

Small-scale

0.559

High

1345354

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

Small-scale

0.559

High

380221

A1BG
Alpha-1B-glycoprotein

1

0

Small-scale

0.537

High

230534

TRAK2
Trafficking kinesin-binding protein 2

1

1

High-throughput

0.536

High

328420

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

High-throughput

0.536

High

370809

ESR1
Estrogen receptor

1

1

High-throughput

0.536

High

505509

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

3

High-throughput

0.536

High

894831

RAB8A
Ras-related protein Rab-8A

1

1

High-throughput

0.536

High

1253449

S22A8
Organic anion transporter 3

1

3

High-throughput

0.536

High

1348206

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

4

High-throughput

0.536

High

1349864

SLAF8
SLAM family member 8

1

1

High-throughput

0.536

High

1357771

TRAK1
Trafficking kinesin-binding protein 1

1

1

High-throughput

0.536

High

685141

STIP1
Stress-induced-phosphoprotein 1

2

3

High-throughput

0.533

High

49428

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

968952

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1048397

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1092784

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1233078

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1242366

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

1253973

HM13
Minor histocompatibility antigen H13

1

0

High-throughput

0.513

High

1254696

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

1266069

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1292139

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

1342998

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

1330687

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

4

Small-scale

0.512

High

476633

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

1326232

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

4

Small-scale

0.501

High

156963

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

802283

GPR3
G-protein coupled receptor 3

1

1

High-throughput

0.489

High

1283479

SPSB4
SPRY domain-containing SOCS box protein 4

1

1

High-throughput

0.489

High

1318479

CD244
Natural killer cell receptor 2B4

1

1

High-throughput

0.489

High

231182

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.479

High

243682

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.479

High

259486

NIPS2
Protein NipSnap homolog 2

1

1

Small-scale

0.479

High

317385

PCNT
Pericentrin

1

1

High-throughput

0.479

High

573546

TCPA
T-complex protein 1 subunit alpha

1

4

High-throughput

0.479

High

737540

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

771109

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.479

High

803825

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.479

High

821475

TCPE
T-complex protein 1 subunit epsilon

1

6

High-throughput

0.479

High

826957

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.479

High

843446

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.479

High

845384

RAB7A
Ras-related protein Rab-7a

1

2

High-throughput

0.479

High

943558

TCPB
T-complex protein 1 subunit beta

1

5

High-throughput

0.479

High

972615

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

3

High-throughput

0.479

High

1020622

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

Small-scale

0.479

High

1053272

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.479

High

1136937

MIC10
MICOS complex subunit MIC10

1

2

Small-scale

0.479

High

1190140

MAVS
Mitochondrial antiviral-signaling protein

1

1

High-throughput

0.479

High

1218412

MFN1
Mitofusin-1

1

1

Small-scale

0.479

High

1220715

MIRO2
Mitochondrial Rho GTPase 2

1

2

High-throughput

0.479

High

1270027

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1297499

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1302900

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1303133

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.479

High

1305158

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

1306759

TCPH
T-complex protein 1 subunit eta

1

5

High-throughput

0.479

High

1308573

NIPS1
Protein NipSnap homolog 1

1

1

Small-scale

0.479

High

1313285

MIC26
MICOS complex subunit MIC26

1

1

High-throughput

0.479

High

1327272

CLPB
Mitochondrial disaggregase

1

2

High-throughput

0.479

High

1328844

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

2

High-throughput

0.479

High

1377903

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

1377924

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.479

High

643421

HMGB2
High mobility group protein B2

1

1

High-throughput

0.464

High

127078

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

130635

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

153489

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.458

High

204092

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

274663

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

276907

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

298926

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

339195

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

418832

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

786206

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

921085

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.458

High

949191

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1030659

CLN3
Battenin

1

0

Small-scale

0.458

High

1036542

MTM1
Myotubularin

1

0

High-throughput

0.458

High

1066942

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1074676

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1083066

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

1140511

MIC13
MICOS complex subunit MIC13

1

0

High-throughput

0.458

High

1183273

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1268996

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1283987

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

Small-scale

0.458

High

1289320

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

1294365

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1326626

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1329831

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1330579

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1334193

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

1335148

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1343518

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.458

High

1344112

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1347368

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

1347745

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1356702

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

1377668

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

306369

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

4

Small-scale

0.457

High

1315817

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

4

Small-scale

0.457

High

61910

MP3B2
Microtubule-associated proteins 1A/1B light chain 3 beta 2

1

4

Small-scale

0.437

High

147300

TXND9
Thioredoxin domain-containing protein 9

1

3

High-throughput

0.437

High

202697

TXNL1
Thioredoxin-like protein 1

1

1

High-throughput

0.437

High

309188

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

828071

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

2

High-throughput

0.437

High

909396

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

970098

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

1032896

PHLP
Phosducin-like protein

1

3

High-throughput

0.437

High

1199722

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.437

High

1297284

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.437

High

1313252

TCAB1
Telomerase Cajal body protein 1

1

1

High-throughput

0.437

High

1316187

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.437

High

1329458

PDCL3
Phosducin-like protein 3

1

3

High-throughput

0.437

High

1332527

RPAP3
RNA polymerase II-associated protein 3

1

2

High-throughput

0.437

High

1342221

WDR6
tRNA

1

1

High-throughput

0.437

High

1176

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

1343854

ANLN
Anillin

2

0

High-throughput

0.305

High

838378

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.282

High

923888

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

0

High-throughput

0.279

Low

1017267

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.279

Low

1198447

T150A
Transmembrane protein 150A

1

0

High-throughput

0.279

Low

1202414

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.279

Low

1202764

P2RY8
P2Y purinoceptor 8

1

0

High-throughput

0.279

Low

1251344

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.279

Low

1262143

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.279

Low

1348135

CLC5A
C-type lectin domain family 5 member A

1

0

High-throughput

0.279

Low

1377923

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

177415

HDAC3
Histone deacetylase 3

1

0

High-throughput

0.249

Low

246066

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.249

Low

330040

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

348351

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

422318

NFL
Neurofilament light polypeptide

1

0

High-throughput

0.249

Low

554156

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652715

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721881

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

901764

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.249

Low

1017474

CDC20
Cell division cycle protein 20 homolog

1

0

High-throughput

0.249

Low

1036245

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1063710

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

1101397

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1119686

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1124472

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

1166105

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1172431

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1206096

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.249

Low

1217007

LRC49
Leucine-rich repeat-containing protein 49

1

0

High-throughput

0.249

Low

1217466

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.249

Low

1257049

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

0

High-throughput

0.249

Low

1268043

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

1297661

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1298322

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.249

Low

1304050

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.249

Low

1311114

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.249

Low

1318585

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.249

Low

1327174

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1331106

TRABD
TraB domain-containing protein

1

0

High-throughput

0.249

Low

1331733

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1332820

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1333839

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

1335491

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1336021

MOV10
Helicase MOV-10

1

0

High-throughput

0.249

Low

1345164

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.249

Low

1348315

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

1349196

DTL
Denticleless protein homolog

1

0

High-throughput

0.249

Low

1354998

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

718363

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.232

Low

1044310

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.232

Low

1103107

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024