HitPredict

Interactor 1: TUD (P25823)
Maternal protein tudor
Gene: TUD

Interactor 2: AGO3 (Q7PLK0)
Protein argonaute-3
Gene: AGO3

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26212455, 19959991
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, cosedimentation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043186 - P granule GO:0140965 - secondary piRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2515 Dm			1 867
+	Dm
		284333 TUD_DROME (1-2515): 0: 2198: 100.00		AUB_DROME (71-867): 0: 768: 30.49
+	Dm
		1186008 VRET_DROME (1774-2104): 1.72e-45: 179: 13.54		AGO3_DROME (1-867): 0: 1057: 100.00
+	Dm
		1000947 Q0E910_DROME (427-760): 9.24e-17: 89.7: 13.19		AGO3_DROME (1-867): 0: 1057: 100.00
+	Mm
		1208145 TDRD1_MOUSE (20-827): 1.76e-49: 196: 14.84		PIWL2_MOUSE (69-867): 0: 885: 35.94
+	Dr
		57795 F1R3C5_DANRE (304-778): 8.44e-34: 145: 13.57		PIWL2_DANRE (63-867): 0: 908: 35.86
+	Hs
		1294950 TDRKH_HUMAN (2347-2479): 5.17e-32: 136: 20.14		PIWL1_HUMAN (119-867): 0: 893: 41.18
+	Dr
		57799 TDRD1_DANRE (7-564): 9.59e-23: 109: 14.11		PIWL2_DANRE (63-867): 0: 908: 35.86
+	Mm
		1194349 TDRKH_MOUSE (2347-2479): 2.55e-29: 127: 19.42		PIWL1_MOUSE (58-867): 0: 885: 38.30
+	Hs
		1183008 SND1_HUMAN (2260-2502): 3.96e-25: 116: 16.54		PIWL1_HUMAN (119-867): 0: 893: 41.18
+	Mm
		1176477 SND1_MOUSE (2260-2491): 2.5e-26: 120: 16.18		PIWL1_MOUSE (58-867): 0: 885: 38.30
+	Dr
		57794 F1QTF8_DANRE (1288-1491): 6.75e-15: 83.6: 17.14		PIWL2_DANRE (63-867): 0: 908: 35.86
+	Dr
		1123241 TDRD1_DANRE (7-564): 9.59e-23: 109: 14.11		PIWL1_DANRE (119-867): 0: 879: 38.47
+	Rn
		1146473 SND1_RAT (2260-2491): 2.74e-26: 120: 16.18		AGO2_RAT (100-859): 0: 856: 20.84
+	Hs
		1189716 TDRKH_HUMAN (2347-2479): 5.17e-32: 136: 20.14		PIWL4_HUMAN (119-867): 0: 817: 36.05
+	Dm
		284352 VRET_DROME (1774-2104): 1.72e-45: 179: 13.54		AUB_DROME (71-867): 0: 768: 30.49
+	Dm
		1363182 VRET_DROME (1774-2104): 1.72e-45: 179: 13.54		PIWI_DROME (64-867): 0: 767: 31.07
+	Ce
		108514 Q19328_CAEEL (1323-1501): 2.57e-14: 81.2: 19.78		G5EGR6_CAEEL (68-859): 0: 822: 18.73
+	Dm
		284339 Q0E910_DROME (427-760): 9.24e-17: 89.7: 13.19		AUB_DROME (71-867): 0: 768: 30.49
+	Dm
		1369536 SND1_DROME (1247-1451): 7.54e-17: 89.7: 17.79		PIWI_DROME (64-867): 0: 767: 31.07
+	Dm
		1374519 SND1_DROME (1247-1451): 7.54e-17: 89.7: 17.79		AGO2_DROME (120-864): 0: 606: 19.36