HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20347421
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 236
+	Hs
		639701 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		639719 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		639710 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		1206094 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		UB2D4_HUMAN (9-167): 3e-71: 216: 32.50
+	Hs
		849363 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		919776 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		895841 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		587507 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		587492 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		829062 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		UBE2A_HUMAN (9-157): 1.04e-26: 102: 38.26