HitPredict

Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: BTG2 (P78543)
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)
Gene: BTG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005829 - cytosol GO:0017148 - negative regulation of translation GO:0060213 - positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2376 Hs			1 158
+	Hs
		63981 CNOT1_HUMAN (1-2376): 0: 3468: 100.00		TOB1_HUMAN (9-123): 4e-57: 183: 42.61
+	Hs
		64011 CNOT1_HUMAN (1-2376): 0: 3468: 100.00		TOB2_HUMAN (9-123): 3.83e-53: 173: 40.87
+	Hs
		64014 CNOT1_HUMAN (1-2376): 0: 3468: 100.00		BTG3_HUMAN (9-116): 2.97e-44: 147: 43.64