Protein: TOB1
Protein Tob1 (Transducer of erbB-2 1)

Gene: TOB1
Organism: Homo sapiens
Interactions: 54
UniProt ID: P50616

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008285 - negative regulation of cell population proliferation
GO:0010468 - regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897476

CNOT7
CCR4-NOT transcription complex subunit 7

10

20

Small-scale

0.974

High

897475

CNOT8
CCR4-NOT transcription complex subunit 8

2

20

High-throughput

0.811

High

63981

CNOT1
CCR4-NOT transcription complex subunit 1

4

3

Small-scale

0.704

High

273837

CNOT3
CCR4-NOT transcription complex subunit 3

3

3

Small-scale

0.675

High

897469

CNO6L
CCR4-NOT transcription complex subunit 6-like

3

5

Small-scale

0.675

High

550186

PABP1
Polyadenylate-binding protein 1

3

3

Small-scale

0.674

High

897464

RAVR1
Ribonucleoprotein PTB-binding 1

3

3

Small-scale

0.662

High

897472

CNO10
CCR4-NOT transcription complex subunit 10

3

1

Small-scale

0.662

High

897474

CNOT2
CCR4-NOT transcription complex subunit 2

3

3

Small-scale

0.662

High

897467

CNOT9
CCR4-NOT transcription complex subunit 9

3

0

Small-scale

0.634

High

897471

TB182
182 kDa tankyrase-1-binding protein

3

0

Small-scale

0.634

High

897457

FHL2
Four and a half LIM domains protein 2

2

1

High-throughput

0.628

High

897477

CNO11
CCR4-NOT transcription complex subunit 11

2

2

High-throughput

0.628

High

897478

CNOT6
CCR4-NOT transcription complex subunit 6

2

5

High-throughput

0.611

High

332292

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.602

High

897454

TADBP
TAR DNA-binding protein 43

2

4

Small-scale

0.588

High

897465

CPEB3
Cytoplasmic polyadenylation element-binding protein 3

1

7

Small-scale

0.586

High

703503

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.586

High

853770

MK09
Mitogen-activated protein kinase 9

1

3

Small-scale

0.578

High

897459

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

Small-scale

0.578

High

132451

CDC7
Cell division cycle 7-related protein kinase

1

1

Small-scale

0.561

High

897461

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

9

Small-scale

0.561

High

897458

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.541

High

715487

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

Small-scale

0.537

High

897468

SCMH1
Polycomb protein SCMH1

1

0

High-throughput

0.518

High

897473

DTL
Denticleless protein homolog

1

1

Small-scale

0.501

High

442271

GELS
Gelsolin

1

0

High-throughput

0.493

High

421740

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

181864

SMAD9
Mothers against decapentaplegic homolog 9

1

12

Small-scale

0.479

High

325736

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

Small-scale

0.479

High

764554

CTNB1
Catenin beta-1

1

2

Small-scale

0.479

High

897451

SMAD3
Mothers against decapentaplegic homolog 3

1

12

Small-scale

0.479

High

897453

CAF1A
Chromatin assembly factor 1 subunit A

1

1

Small-scale

0.479

High

897455

SKP2
S-phase kinase-associated protein 2

1

3

Small-scale

0.479

High

897456

SMAD4
Mothers against decapentaplegic homolog 4

1

12

Small-scale

0.479

High

897460

SMAD1
Mothers against decapentaplegic homolog 1

1

12

Small-scale

0.479

High

897462

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

2

Small-scale

0.479

High

897470

SMAD5
Mothers against decapentaplegic homolog 5

1

12

Small-scale

0.479

High

651226

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

141378

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

Small-scale

0.445

High

608504

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

Small-scale

0.445

High

650647

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

Small-scale

0.445

High

726743

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

3

Small-scale

0.445

High

729009

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

6

Small-scale

0.445

High

729182

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

6

Small-scale

0.445

High

897447

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

6

Small-scale

0.445

High

897448

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

6

Small-scale

0.445

High

897450

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.426

High

897452

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

Small-scale

0.426

High

94348

D6R9H6
CCR4-NOT transcription complex subunit 6

1

5

High-throughput

0.407

High

897463

OBI1
ORC ubiquitin ligase 1

2

0

High-throughput

0.328

High

897449

CORO7
Coronin-7

1

0

Small-scale

0.299

High

650092

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

897466

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025