Interactor 1: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Interactor 2: EDC3 (Q96F86)
Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)
Gene: EDC3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 25416956, 26186194, 28514442, 29510985, 19285948, 23535175, 32296183, 29395067, 24981860, 33961781, 35271311, 16364915, 31515488, 29892012, unassigned1304, 26184334
Identification Methods two hybrid, affinity chromatography technology, pull down, x-ray crystallography, proximity labelling technology, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FDF~Helicase_C
Common GO terms GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0033962 - P-body assembly
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 483
Hs

1 508
+ Dm
+ Sc

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Last updated: 15 Jul 2024