HitPredict

Interactor 1: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Interactor 2: LS14B (Q9BX40)
Protein LSM14 homolog B (RNA-associated protein 55B) (hRAP55B)
Gene: LSM14B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.940

Property	Details
Experiments	35271311, 26186194, 28514442, 29395067, 24778252, 26184334
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FDF~Helicase_C
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 385
+	Hs
		134191 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		LS14B_HUMAN (1-385): 7.86e-179: 504: 100.00
+	Hs
		640548 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		LS14A_HUMAN (4-351): 1.25e-126: 374: 49.25
+	Hs
		134126 DDX3X_HUMAN (8-473): 3.18e-131: 396: 25.26		LS14A_HUMAN (4-351): 1.25e-126: 374: 49.25
+	Ce
		1280152 CGH1_CAEEL (58-481): 2.86e-159: 459: 70.05		LS14H_CAEEL (4-347): 8.19e-57: 190: 32.96
+	Sc
		761971 DHH1_YEAST (67-472): 8.45e-132: 392: 67.98		SCD6_YEAST (7-357): 5.37e-69: 222: 26.61
+	Dm
		612749 DDX6_DROME (47-471): 1.33e-158: 459: 71.77		Q9VTZ0_DROME (4-104): 2.54e-31: 127: 57.43
+	At
		1277679 RH6_ARATH (41-469): 8e-134: 398: 67.37		DCP5_ARATH (77-352): 3.01e-14: 76.2: 22.86