Protein: PBX3
Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3)

Gene: PBX3
Organism: Homo sapiens
Interactions: 87
UniProt ID: P40426

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 - eye development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

163417

MEIS2
Homeobox protein Meis2

4

19

High-throughput

0.892

High

253007

LMX1B
LIM homeobox transcription factor 1-beta

3

10

High-throughput

0.861

High

823930

PKNX1
Homeobox protein PKNOX1

2

20

Small-scale

0.785

High

823927

MAGA1
Melanoma-associated antigen 1

4

7

High-throughput

0.695

High

823934

HME1
Homeobox protein engrailed-1

1

20

High-throughput

0.691

High

724990

HXA9
Homeobox protein Hox-A9

1

20

Small-scale

0.681

High

823938

MB211
Putative nucleotidyltransferase MAB21L1

3

9

High-throughput

0.667

High

823991

MB212
Protein mab-21-like 2

3

9

High-throughput

0.667

High

604773

HXB8
Homeobox protein Hox-B8

1

20

Small-scale

0.647

High

51402

FSD2
Fibronectin type III and SPRY domain-containing protein 2

3

4

High-throughput

0.635

High

823926

PBX3
Pre-B-cell leukemia transcription factor 3

1

20

High-throughput

0.621

High

823973

PKNX2
Homeobox protein PKNOX2

1

20

High-throughput

0.618

High

823952

ATRAP
Type-1 angiotensin II receptor-associated protein

4

2

High-throughput

0.616

High

725217

TLX1
T-cell leukemia homeobox protein 1

1

20

Small-scale

0.590

High

139389

VMA5A
von Willebrand factor A domain-containing protein 5A

2

4

High-throughput

0.574

High

823947

F222A
Protein FAM222A

2

5

High-throughput

0.574

High

823958

CE024
UPF0461 protein C5orf24

2

5

High-throughput

0.574

High

823960

DAAF8
Dynein axonemal assembly factor 8

2

5

High-throughput

0.574

High

823972

CC120
Coiled-coil domain-containing protein 120

2

6

High-throughput

0.574

High

563352

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.541

High

823942

ZNHI3
Zinc finger HIT domain-containing protein 3

1

1

High-throughput

0.541

High

133093

FOXE1
Forkhead box protein E1

1

16

High-throughput

0.536

High

823939

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

823954

TSH1
Teashirt homolog 1

1

6

High-throughput

0.536

High

823984

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.536

High

823935

TRAF1
TNF receptor-associated factor 1

2

5

High-throughput

0.533

High

823968

MAL2
Protein MAL2

2

4

High-throughput

0.533

High

823990

PRAF1
Prenylated Rab acceptor protein 1

2

1

High-throughput

0.533

High

823985

TMOD3
Tropomodulin-3

1

3

High-throughput

0.489

High

823937

CENPR
Centromere protein R

1

3

High-throughput

0.481

High

823951

CPLX2
Complexin-2

1

1

High-throughput

0.481

High

823959

TMCO2
Transmembrane and coiled-coil domain-containing protein 2

1

1

High-throughput

0.481

High

823963

ZN655
Zinc finger protein 655

1

1

High-throughput

0.481

High

823975

SIN3A
Paired amphipathic helix protein Sin3a

1

7

High-throughput

0.481

High

823979

INP5K
Inositol polyphosphate 5-phosphatase K

1

1

High-throughput

0.481

High

823988

MAGC2
Melanoma-associated antigen C2

1

7

High-throughput

0.481

High

371362

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

405863

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

823974

CIC
Protein capicua homolog

1

14

High-throughput

0.479

High

823976

TBX5
T-box transcription factor TBX5

1

15

High-throughput

0.479

High

823977

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.458

High

71162

HIG1C
HIG1 domain family member 1C

1

1

High-throughput

0.439

High

178728

SCAM1
Secretory carrier-associated membrane protein 1

1

1

High-throughput

0.439

High

253060

PLIN3
Perilipin-3

1

1

High-throughput

0.439

High

261114

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.439

High

339212

SFT2B
Vesicle transport protein SFT2B

1

1

High-throughput

0.439

High

447698

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.439

High

469466

SYPH
Synaptophysin

1

3

High-throughput

0.439

High

640573

MK
Midkine

1

1

High-throughput

0.439

High

823928

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

1

High-throughput

0.439

High

823929

ARFP2
Arfaptin-2

1

4

High-throughput

0.439

High

823931

CAV3
Caveolin-3

1

1

High-throughput

0.439

High

823932

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.439

High

823933

DCE2
Glutamate decarboxylase 2

1

1

High-throughput

0.439

High

823936

BIK
Bcl-2-interacting killer

1

1

High-throughput

0.439

High

823940

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.439

High

823941

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.439

High

823943

SYPL1
Synaptophysin-like protein 1

1

3

High-throughput

0.439

High

823944

TPD53
Tumor protein D53

1

1

High-throughput

0.439

High

823945

INSY1
Inhibitory synaptic factor 1

1

1

High-throughput

0.439

High

823946

TM196
Transmembrane protein 196

1

1

High-throughput

0.439

High

823948

MIC13
MICOS complex subunit MIC13

1

1

High-throughput

0.439

High

823949

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

1

High-throughput

0.439

High

823950

RHBD2
Rhomboid domain-containing protein 2

1

1

High-throughput

0.439

High

823953

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

1

1

High-throughput

0.439

High

823955

RHEX
Regulator of hemoglobinization and erythroid cell expansion protein

1

1

High-throughput

0.439

High

823956

K1C27
Keratin, type I cytoskeletal 27

1

3

High-throughput

0.439

High

823957

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

1

High-throughput

0.439

High

823961

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

6

High-throughput

0.439

High

823962

F177A
Protein FAM177A1

1

1

High-throughput

0.439

High

823964

GBP7
Guanylate-binding protein 7

1

1

High-throughput

0.439

High

823965

FADS6
Fatty acid desaturase 6

1

1

High-throughput

0.439

High

823966

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.439

High

823967

BSND
Barttin

1

1

High-throughput

0.439

High

823969

TRI44
Tripartite motif-containing protein 44

1

4

High-throughput

0.439

High

823970

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

1

High-throughput

0.439

High

823971

MTEF3
Transcription termination factor 3, mitochondrial

1

2

High-throughput

0.439

High

823978

DESI2
Deubiquitinase DESI2

1

1

High-throughput

0.439

High

823980

NUDT9
ADP-ribose pyrophosphatase, mitochondrial

1

1

High-throughput

0.439

High

823981

LIME1
Lck-interacting transmembrane adapter 1

1

1

High-throughput

0.439

High

823982

RPRM
Protein reprimo

1

1

High-throughput

0.439

High

823983

RN186
E3 ubiquitin-protein ligase RNF186

1

1

High-throughput

0.439

High

823986

TV23B
Golgi apparatus membrane protein TVP23 homolog B

1

1

High-throughput

0.439

High

823987

TFP11
Tuftelin-interacting protein 11

1

2

High-throughput

0.439

High

823989

CIDEB
Lipid transferase CIDEB

1

1

High-throughput

0.439

High

823992

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

1

High-throughput

0.439

High


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Last updated: 11Aug2025