HitPredict

Interactor 1: CDC20 (P26309)
APC/C activator protein CDC20 (Cell division control protein 20)
Gene: CDC20

Interactor 2: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	11805837, 12887895
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 610 Sc			1 527
+	Sc
		640850 CDC20_YEAST (1-610): 1.51e-134: 407: 100.00		TCPH_YEAST (3-527): 0: 537: 32.26
+	Sc
		640841 CDC20_YEAST (1-610): 1.51e-134: 407: 100.00		TCPG_YEAST (2-522): 0: 527: 27.05
+	Sc
		760659 CDH1_YEAST (111-557): 2.02e-98: 313: 28.76		TCPB_YEAST (1-527): 0: 553: 100.00
+	Sc
		792390 CDH1_YEAST (111-557): 2.02e-98: 313: 28.76		TCPH_YEAST (3-527): 0: 537: 32.26
+	Sc
		760773 AMA1_YEAST (172-558): 6.88e-102: 322: 22.10		TCPG_YEAST (2-522): 0: 527: 27.05
+	Sc
		760779 CDH1_YEAST (111-557): 2.02e-98: 313: 28.76		TCPG_YEAST (2-522): 0: 527: 27.05
+	Hs
		1306704 NLE1_HUMAN (115-457): 7.93e-66: 224: 12.18		TCPH_HUMAN (2-517): 0: 570: 34.36
+	Hs
		826807 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Hs
		943508 NLE1_HUMAN (115-457): 7.93e-66: 224: 12.18		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Hs
		943393 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Hs
		821437 NLE1_HUMAN (115-457): 7.93e-66: 224: 12.18		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Hs
		573406 FBXW7_HUMAN (329-608): 1.28e-60: 216: 14.54		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		943403 SNR40_HUMAN (371-610): 1.02e-48: 175: 17.77		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Hs
		826848 TBL1Y_HUMAN (9-371): 4.35e-40: 155: 10.72		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Hs
		573412 SNR40_HUMAN (371-610): 1.02e-48: 175: 17.77		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		821355 SNR40_HUMAN (371-610): 1.02e-48: 175: 17.77		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Hs
		943437 TBL1Y_HUMAN (9-371): 4.35e-40: 155: 10.72		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Hs
		573446 TBL1Y_HUMAN (9-371): 4.35e-40: 155: 10.72		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		821387 TBL1Y_HUMAN (9-371): 4.35e-40: 155: 10.72		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Sc
		640846 CDC20_YEAST (1-610): 1.51e-134: 407: 100.00		TCPE_YEAST (5-515): 1.24e-77: 256: 35.09